Dataset of histone H3K4me2 modified genes in the liver of female Sprague-Dawley rats with chronic antipsychotic drugs of olanzapine or clozapine.

Yueqing Su, Jiamei Lian, Chao Deng

Abstract read

In one paragraph

Article in Data in brief, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Yueqing SuFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Jiamei LianSchool of Medical, Indigenous and Health Sciences, and Molecular Horizons, University of Wollongong, Wollongong, NSW 2522, Australia.

Chao DengSchool of Medical, Indigenous and Health Sciences, and Molecular Horizons, University of Wollongong, Wollongong, NSW 2522, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic histone modifications have been found to be associated with the development of metabolic disorders. However, the potential contribution of these modifications to metabolic disturbances induced by chronic treatment with second-generation antipsychotic drugs (SGAs) remains unclear. This dataset presents chromatin immunoprecipitation (ChIP) data on H3K4me methylation in hepatic tissue of rats treated with olanzapine or clozapine for 9 weeks for a comprehensive view of the effects of SGAs on H3K4me methylation in an animal model. It offers new insights into the epigenetic mechanisms underlying SGAs-induced metabolic side effects.

Indexed as

ChIP-SequencingClozapineH3K4meLiverOlanzapineSecond generation antipsychotic drugs

Identifiers

PMID40124298

DOI10.1016/j.dib.2025.111425

PMCPMC11928814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.