Evidence map›Paper›PMID 40124247›Full record

ReviewFrontiers in bioengineering and biotechnology2025

Very small embryonic-like stem cells (VSELs) on the way for potential applications in regenerative medicine.

Kannathasan Thetchinamoorthy, Justyna Jarczak, Patrycja Kieszek, Diana Wierzbicka, Janina Ratajczak, Magdalena Kucia, Mariusz Z Ratajczak

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kannathasan Thetchinamoorthy *Laboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland.
Justyna Jarczak *Laboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland.
Patrycja KieszekLaboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland.
Diana WierzbickaLaboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland.
Janina RatajczakStem Cell Institute at Graham Brown Cancer Center, University of Louisville, Louisville, CO, United States.
Magdalena KuciaLaboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland.
Mariusz Z RatajczakLaboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence has accumulated that adult tissues contain a population of early development stem cells capable of differentiating across germ layers into various types of cells. Our group purified these rare cells, naming them very small embryonic-like stem cells (VSELs). With their broad differentiation potential, VSELs have emerged as a new candidate population for clinical applications. This advancement is now possible due to our recent development of a model for

Indexed as

embryonic stem cellsinduced pluripotent stem cellspluripotent stem cellstissue organ regenerationvery small embryonic-like stem cells (VSELs)

Identifiers

PMID40124247
PMCPMC11926153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.