Evidence map›Paper›PMID 40124071›Full record

ArticleACS omega2025

Assessing Toxicological Safety of EverX Posterior and Filtek Ultimate: An In-Depth Extractable and Leachable Study Under ISO 10993-17 and 10993-18 Standards.

Aysu Aydınoǧlu, Yelda Erdem Hepşenoǧlu, Can Özgür Yalçın, Kadir Saǧır, Yeşim Ölçer Us, Şeyda Erşahan Eroǧlu, Afife Binnaz Hazar Yoruç

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In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aysu AydınoǧluDepartment of Metallurgical and Materials Engineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, 34210 İstanbul, Türkiye.
Yelda Erdem HepşenoǧluDepartment of Endodontics, Faculty of Dentistry, İstanbul Medipol University, 34250 İstanbul, Türkiye.
Can Özgür YalçınDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Karadeniz Technical University, 61080 Trabzon, Türkiye.
Kadir SaǧırDepartment of Materials Science and Technology, Faculty of Science Materials Science and Technology, Turkish-German University, 34820 İstanbul, Türkiye.
Yeşim Ölçer UsDepartment of Prosthodontics, School of Dental Medicine, Bahçeşehir University, 34353 İstanbul, Türkiye.
Şeyda Erşahan EroǧluDepartment of Endodontics, Faculty of Dentistry, İstanbul Medipol University, 34250 İstanbul, Türkiye.
Afife Binnaz Hazar YoruçDepartment of Metallurgical and Materials Engineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, 34210 İstanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study critically evaluates the biocompatibility and toxicological safety of EverX Posterior (eXP) and Filtek Ultimate (FU) dental composites following the International Standardization Organization (ISO) 10993-17:2023 and 10993-18:2020 guidelines. Our research highlights important findings on the depth of cure, water absorption, solubility, and release profiles of organic compounds in these composites using advanced chromatographic techniques. The analysis revealed that both eXP and FU composites are safe for patients regarding extractable and leachable (E&L) compounds, indicating a low risk of adverse biological effects. It was found that eXP and FU had solubilities of 6.062 ± 0.576 and 0.864 ± 0.436 μg/mm

Identifiers

PMID40124071
PMCPMC11923668

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.