Evidence map›Paper›PMID 40124046›Full record

ArticleACS omega2025

Synthesis, Pharmacological Evaluation, and Molecular Modeling of Phthalimide Derivatives as Monoamine Oxidase and Cholinesterase Dual Inhibitors.

Nabiha Abdullah, Fahad Hussain, Naseem Ullah, Humaira Fatima, Muhammad Afaq Tahir, Umer Rashid, Abbas Hassan

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nabiha AbdullahDepartment of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Fahad HussainDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
Naseem UllahDepartment of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Humaira FatimaDepartment of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Muhammad Afaq TahirInstitute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.
Umer RashidDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.ORCID https://orcid.org/0000-0002-2419-3172
Abbas HassanDepartment of Chemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan.ORCID https://orcid.org/0000-0001-6088-431X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia and cognitive decline, associated with synaptic loss and degeneration of cholinergic neurons. New multitarget inhibitors for monoamine oxidase (MAO) and cholinesterase (ChE) enzymes are emerging as a potential treatment strategy for AD. Herein, we synthesized a series of

Identifiers

PMID40124046
PMCPMC11923636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.