Evidence map›Paper›PMID 40124044›Full record

ArticleACS omega2025

Optimized Degradation of Doxycycline in Aqueous Systems Using Calcium Peroxide Nanoparticles via Response Surface Methodology.

Nurul Nazihah Amerhaider Nuar, Siti Nurul Ain Md Jamil, Thomas Shean Yaw Choong, Syazana Ishami Mahadzir, Intan Diana Mat Azmi, Mohd Salahuddin Mohd Basri, Mohamad Rezi Abdul Hamid

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nurul Nazihah Amerhaider NuarDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia (UPM), Serdang, Selangor 43400, Malaysia.ORCID https://orcid.org/0000-0002-7390-361X
Siti Nurul Ain Md JamilDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia (UPM), Serdang, Selangor 43400, Malaysia.
Thomas Shean Yaw ChoongCenter of Sustainable Research, Department of Chemical and Environmental Engineering, Faculty of Engineering, Universiti Putra Malaysia (UPM), Serdang, Selangor 43400, Malaysia.
Syazana Ishami MahadzirDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia (UPM), Serdang, Selangor 43400, Malaysia.
Intan Diana Mat AzmiDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia (UPM), Serdang, Selangor 43400, Malaysia.ORCID https://orcid.org/0000-0002-0168-3232
Mohd Salahuddin Mohd BasriDepartment of Process and Food Engineering, Faculty of Engineering, Universiti Putra Malaysia (UPM), Serdang, Selangor 43400, Malaysia.
Mohamad Rezi Abdul HamidCenter of Sustainable Research, Department of Chemical and Environmental Engineering, Faculty of Engineering, Universiti Putra Malaysia (UPM), Serdang, Selangor 43400, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of antibiotic residues in aqueous systems, particularly doxycycline (DOX), is harmful to the environment and public health. In this study, dextran-coated calcium peroxide nanoparticles (DEX@nCPs(DEX)), Fe(II), and oxalic acid (OA) were combined to improve the heterogeneous Fenton-like degradation of DOX. X-ray photoelectron spectroscopy (XPS) demonstrated the successful synthesis of DEX@nCPs(DEX), showing the presence of Ca, O, and C functional groups associated with dextran. Using response surface methodology with a central composite design (RSM-CCD), the optimal conditions (DEX@nCPs(DEX) dosage: 2 g/L, pH: 5, contact time: 420 min) achieved 90% DOX removal, which was 20% higher than using DEX@nCPs(DEX)/Fe(II) alone. The degradation process followed first-order kinetics with a rate constant of

Identifiers

PMID40124044
PMCPMC11923643

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.