Evidence map›Paper›PMID 40123942›Full record

ArticleMethodist DeBakey cardiovascular journal2025

From Chronic Use of Minocycline to Pigmented Unicuspid Aortic Valve: A Unique Single Case.

Nour B Odeh, Juan M Farina, Pete J Manchen, Kristen A Sell-Dottin, Bryan Barrus

Abstract readCase Reports
In one paragraph

Article in Methodist DeBakey cardiovascular journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nour B OdehMayo Clinic, Phoenix, Arizona, US.ORCID https://orcid.org/0000-0002-9036-9906
Juan M FarinaMayo Clinic, Phoenix, Arizona, US.ORCID https://orcid.org/0000-0002-5824-8485
Pete J ManchenMayo Clinic, Phoenix, Arizona, US.ORCID https://orcid.org/0009-0005-5020-6810
Kristen A Sell-DottinMayo Clinic, Phoenix, Arizona, US.ORCID https://orcid.org/0000-0001-5933-3537
Bryan BarrusMayo Clinic, Phoenix, Arizona, US.ORCID https://orcid.org/0000-0003-3959-8268

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We discuss the case of a 47-year-old female who presented to our institution with progressive exertional shortness of breath. Her history was notable for severe acne medicated with 100 mg oral daily minocycline for 2 years and a presumptive diagnosis of a bicuspid aortic valve. Investigations revealed severe aortic stenosis, prompting a decision for elective aortic valve repair. Intraoperatively, significant calcification of a unicuspid aortic valve, atypically blackened valve, and endocardium of the left ventricle and aorta were visualized.

Indexed as

Anti-Bacterial AgentsAortic ValveAortic Valve StenosisCalcinosisHeart Valve DiseasesMinocyclineBicuspid Aortic Valve DiseaseFemaleHeart Valve Prosthesis ImplantationHumansMiddle AgedSeverity of Illness IndexTreatment OutcomeAnti-Bacterial AgentsMinocyclinealkaptonuriaaortic stenosiscardiovascular hyperpigmentationcardiovascular ochronosisminocyclineminocycline induced hyperpigmentation (MIH)valvular pigmentation

Identifiers

PMID40123942
PMCPMC11927672

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.