ArticleComputational and structural biotechnology journal2025
BGMDB: A curated database linking gut microbiota dysbiosis to brain disorders.
Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Artificial intelligence empowers gut microbiota research in neurodegenerative diseases molecular mechanisms and precision therapy.iScience · 2025Review
- MINERVA-microbiome network research and visualization atlas: a scalable knowledge graph for mapping microbiome-disease associations.Briefings in bioinformatics · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
The gut microbiota is a fundamental component of human health and has been increasingly implicated in the etiology of neurological disorders. Neurotransmitters, acting as key mediators of gut-brain communication, are closely associated with both the progression and therapeutic modulation of brain diseases. Despite significant advancements in microbiome research, the complex interplay between gut microbiota and neurological disorders remains poorly understood, and a comprehensive resource integrating these associations is lacking. To bridge this gap, we developed the Brain Disease Gut Microbiota Database (BGMDB), a rigorously curated repository documenting experimentally validated relationships between gut microbiota and brain diseases. BGMDB encompasses 1419 associations involving 609 gut microbiota taxa and 43 brain disorders, along with 184 tripartite interactions linking brain diseases, neurotransmitters, and microbiota across six neurotransmitter systems. Additionally, BGMDB integrates genetic data from the gutMGene database, allowing users to explore microbiota-mediated genetic associations with brain disease pathology and neuroanatomical alterations. A user-friendly interface enables researchers to navigate relevant information through graphical query tools, comprehensive browsing functionalities, and data retrieval options. Our BGMDB provides an unparalleled resource for advancing mechanistic insights into gut-brain interactions, facilitating novel microbiota-targeted therapeutic strategies for neurological disorders. BGMDB is freely available at: http://bgmdb.online/bgmdb.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.