Evidence map›Paper›PMID 40123794›Full record

ArticleEJHaem2025

Beyond Childhood: Adult and Adolescent Sickle Cell Disease and Outcomes in Northern Ghana.

Kwadwo Faka Gyan, Solomon Gyabaah, Eunice Agyeman Ahmed, Lesley Osei, Mohammed Najeeb Naabo, Michael Asiedu Owiredu, Yaw Obeng Opare-Addo, Jessey Mahama Holu, Ohene Kwaku Opare-Sem

Abstract read
In one paragraph

Article in EJHaem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kwadwo Faka GyanKomfo Anokye Teaching Hospital Kumasi Ghana.
Solomon GyabaahKomfo Anokye Teaching Hospital Kumasi Ghana.ORCID https://orcid.org/0000-0002-5941-9733
Eunice Agyeman AhmedKomfo Anokye Teaching Hospital Kumasi Ghana.
Lesley OseiKomfo Anokye Teaching Hospital Kumasi Ghana.
Mohammed Najeeb NaaboKomfo Anokye Teaching Hospital Kumasi Ghana.ORCID https://orcid.org/0009-0009-6654-2623
Michael Asiedu OwireduKomfo Anokye Teaching Hospital Kumasi Ghana.
Yaw Obeng Opare-AddoKomfo Anokye Teaching Hospital Kumasi Ghana.
Jessey Mahama HoluKomfo Anokye Teaching Hospital Kumasi Ghana.
Ohene Kwaku Opare-SemKomfo Anokye Teaching Hospital Kumasi Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Adults and adolescents face different barriers to healthcare utilization compared to children. Objective: To describe adult and adolescent sickle cell disease (SCD) and outcomes in northern Ghana. Methods: This was a retrospective cohort study of SCD patients aged 13 years and above, admitted between January 1, 2021 and December 31, 2022 at the Komfo Anokye Teaching Hospital. The data was summarized with descriptive statistics and a multivariate logistics regression analysis was fitted to identify factors independently associated with prolonged hospital stay of more than 4 days. Results: Of the 326 admissions, 68.9% regularly attended their sickle cell clinics. Approximately 3% of all admissions into the internal medicine ward were due to SCD. Commonest complications observed were painful vaso-occlusive crisis (VOC) (78.1%), infection (51.2%), and hyperhemolysis (24.0%). Presented as adjusted odds ratio (95% CI), the predictors of prolonged hospital stay were: presence of comorbidities, 2.71 [(1.28, 5.97), Conclusion: SCD and its related complications constitute a significant proportion of all admissions into the adult medical ward. Approximately one in every three Ghanaian adult and adolescent SCD patients does not regularly attend the SCD clinic. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.

Indexed as

admissionadults and adolescentsGhanaoutcomessickle cell disease

Identifiers

PMID40123794
PMCPMC11927018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.