ArticleInternational journal of rheumatic diseases2025
Relationship Between Sarcopenia, Femoral Cartilage Thickness, and Knee Osteoarthritis: Case-Control Study.
Article in International journal of rheumatic diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Higher Prevalence of Sarcopenia in Knee Osteoarthritis and Its Association with Femoral Intercondylar Cartilage Thickness and Functional Outcomes.Life (Basel, Switzerland) · 2025Article
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Authors and funding
3 authors.
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Abstract
objectiveThis study aims to evaluate the association between femoral cartilage thickness (FCT) and knee osteoarthritis (KO) in individuals with sarcopenia and pre-sarcopenia, highlighting the potential role of FCT in the relationship between sarcopenia and KO. STUDY
designA cross-sectional study including 80 individuals (23 pre-sarcopenia, 21 sarcopenia, and 36 healthy controls) aged 40-75 years was conducted. Using ultrasound (US), FCT was measured, and KO prevalence was compared among the three groups. Logistic regression analyses were performed to determine the predictors of KO and sarcopenia, and ROC analysis was conducted to estimate sarcopenia from FCT measurements.
resultsThe mean age of the 80 participants (55 females, 25 males) was 62.22 ± 7.56 years. The sarcopenia group had significantly lower medial and lateral FCT than the control group (all p < 0.01). Logistic regression analysis indicated that age and sarcopenia were significant predictors of KO (all p < 0.01). Multinomial logistic regression showed that KO and medial FCT were significant predictors of sarcopenia (all p < 0.05). ROC analysis demonstrated that medial FCT effectively predicted sarcopenia (p = 0.001, AUC = 0.736).
conclusionsThe results of this study showed that FCT was reduced, and KO prevalence was increased in sarcopenia patients. Additionally, age and sarcopenia were predictors for KO, while KO and decreased medial FCT were predictors of sarcopenia. These findings suggest that sarcopenia may influence FCT through mechanical effects related to muscle strength loss and potentially other mechanisms, making it a potential risk factor for KO.
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