ArticleJournal of aging and health2025
Subjective Cognitive Impairment (SCI) and Future Dementia Risk in the National Health and Aging Trends Study (NHATS) During 2012-2019.
Article in Journal of aging and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Is social connection the key to prevention? Educational attainment, incident dementia, and the role of later-life social engagement.Innovation in aging · 2026Article
- Objective Assessment of Cognition for Detecting Subjective Cognitive Decline Is More Accurate than Subjective Estimations: The Role of Trait Affect.Journal of Intelligence · 2025Article
- Early Detection of Cognitive Decline: Executive Functioning Index R4Alz-pc Predicts Memory-Related Concerns in Community Adults.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
BackgroundSubjective cognitive impairment (SCI), assessed in national surveys, offers potential for dementia monitoring and early detection. However, its causal link to dementia risk remains unclear.ObjectiveTo evaluate whether SCI causally affects dementia risk in U.S. older adults (≥65 years), considering mortality as a competing risk.MethodsUsing data from 1622 dementia-free older adults in the National Health and Aging Trends Study (NHATS) during 2011-2019, we estimated total, direct, and separable effects of SCI on dementia and mortality risks.ResultsSCI was reported by 7.6% at baseline and associated with a twofold increased dementia risk over 8 years (RR: 1.95, 95% CI: 1.07-3.07) and lower mortality risk (RR: 0.31, 95% CI: 0.10-0.67). Direct effect analysis indicated a potential direct causal link between SCI and dementia.ConclusionsSCI predicts dementia onset and inversely affects mortality, highlighting the importance of early detection and precise analytic approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.