Evidence map›Paper›PMID 40123186›Full record

ArticleJournal of aging and health2025

Longitudinal Engagement in Modifiable Lifestyle Behaviors and Racial-Ethnic Differences in Dementia Risk.

Roger Wong, Tatiana Mikhailova, Darrell Hudson, Sojung Park, Shenyang Guo

Abstract read
In one paragraph

Article in Journal of aging and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roger WongDepartment of Public Health and Preventive Medicine, Norton College of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA.ORCID 0000-0002-2243-1990
Tatiana MikhailovaDepartment of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA.ORCID 0000-0003-4169-1322
Darrell HudsonBrown School, Washington University in St Louis, St Louis, MO, USA.
Sojung ParkBrown School, Washington University in St Louis, St Louis, MO, USA.ORCID 0000-0002-1381-7736
Shenyang GuoBrown School, Washington University in St Louis, St Louis, MO, USA.

Funding

The Johns Hopkins Alzheimer's Disease Resource Center for Minority Aging Research - Research Ed ComponentP30AG059298 · NIA · JOHNS HOPKINS UNIVERSITY · PI Joseph John Gallo, ROLAND J. THORPE · 2018 to 2026
$7.1M
Lifestyle Behaviors and Racial Differences in Alzheimer's DiseaseR36AG061426 · NIA · WASHINGTON UNIVERSITY · PI WONG, ROGER · 2019 to 2020
$99k
NIA NIH HHS P30 AG059298NIA NIH HHS R36 AG061426
6 · The paper itself

Abstract

ObjectivesThe objective was to examine racial-ethnic differences in longitudinal engagement for lifestyle behaviors and moderating role of race-ethnicity between lifestyle behaviors and dementia risk.MethodsWe analyzed 2011-2021 National Health and Aging Trends Study data, a nationally representative U.S. sample of 6155 White, Black, Hispanic, and Asian older adults aged 65+. Cox models regressed dementia on the interaction between lifestyle behaviors (physical activity, smoking, and social contacts) and race-ethnicity.ResultsOnly smoking was associated with about a 45% higher dementia risk (aHR = 1.45, 95% CI = 1.11-1.89). On average, Black and Hispanic respondents exhibited less frequent physical activity and social contacts, along with more frequent smoking. There was one significant interaction; more social contacts were associated with lower dementia risk among Asian respondents (aHR = 0.16, 95% CI = 0.05-0.55).DiscussionRacial-ethnic differences in lifestyle behaviors should be considered when addressing dementia disparities. Future research needs to explore the relationship between social contacts and lower dementia risk among Asian older adults.

Indexed as

DementiaEthnicityLife StyleAgedAged, 80 and overAsianBlack or African AmericanExerciseFemaleHealth BehaviorHispanic or LatinoHumansLongitudinal StudiesMaleRisk FactorsSmokingdementiaphysical activityracesmokingsocial engagement

Identifiers

PMID40123186
PMCPMC12081203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.