Evidence map›Paper›PMID 40123108›Full record

ArticleThe American journal of sports medicine2025

Defining the Minimal Clinically Important Improvement, Substantial Clinical Benefit, and Patient Acceptable Symptom State for the iHOT-12, HOOS, and HOOS

Abby L Cheng, Christopher M Radlicz, Madeline M Pashos, Julia B Huecker, Karen Steger-May, Heidi Prather, John C Clohisy, Marcie Harris-Hayes

Abstract read
In one paragraph

Article in The American journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Hip joint power during a single leg squat is related to patient-reported function, physical activity, and symptom duration in individuals with chronic hip-Related pain.Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine · 2026
    Observational
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abby L ChengDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA.ORCID 0000-0002-8166-0806
Christopher M RadliczDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA.
Madeline M PashosDepartment of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Julia B HueckerCenter for Biostatistics and Data Science, Washington University School of Medicine, St Louis, Missouri, USA.
Karen Steger-MayCenter for Biostatistics and Data Science, Washington University School of Medicine, St Louis, Missouri, USA.
Heidi PratherDepartment of Rehabilitation Medicine, Weill Cornell Medical College, New York, New York, USA.
John C ClohisyDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA.
Marcie Harris-HayesDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri, USA.ORCID 0000-0003-4274-1651

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational Sciences (TL1)TL1TR002344 · NCATS · WASHINGTON UNIVERSITY · PI Jay F. Piccirillo · 2017 to 2026
$8.5M
Predicting patient-reported outcomes in patients with pre-arthritic hip disordersK23AR074520 · NIAMS · WASHINGTON UNIVERSITY · PI CHENG, ABBY LING-LEE · 2019 to 2023
$881k
NCATS NIH HHS TL1 TR002344NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NIAMS NIH HHS K23 AR074520
6 · The paper itself

Abstract

backgroundScore cutoffs of clinically important outcome values such as the minimal clinically important improvement (MCII), substantial clinical benefit (SCB), and Patient Acceptable Symptom State (PASS) are population and treatment specific. In patients with nonarthritic hip-related pain, numerous score cutoffs have been calculated for use after surgical treatment, but they have not been established for patients who pursue nonoperative care. PURPOSE: To determine the MCII, SCB, and PASS score cutoffs for the 12-item International Hip Outcome Tool (iHOT-12), the Hip Disability and Osteoarthritis Outcome Score (HOOS), and an 8-item abbreviated version of the HOOS (HOOS STUDY

designCohort study; Level of evidence, 4.

methodsThe cohort included 15- to 40-year-old patients who were diagnosed with nonarthritic hip-related pain by a surgical or nonsurgical orthopaedic clinician and were advised to pursue nonoperative management at the time of evaluation. At baseline and 12-month follow-up, patients completed the iHOT-12, HOOS, and HOOS

resultsAmong 61 patients (mean age, 28 ± 8 years; 50 [82%] female), for the iHOT-12, the MCII score cutoff was 14, the SCB score cutoff was 18, and the PASS score cutoff was 63. For the HOOS subscales, the MCII score cutoffs ranged from 4 (Activities of Daily Living) to 13 (Sport and Recreation), the SCB score cutoffs ranged from 10 (Symptoms and Activities of Daily Living) to 25 (Quality of Life), and the PASS score cutoffs ranged from 50 (Quality of Life) to 87 (Activities of Daily Living). For the HOOS

conclusionThese clinically important outcome values can assist clinicians and researchers with interpreting patients' clinical change during nonoperative treatment for nonarthritic hip-related pain.

Indexed as

ArthralgiaHip JointMinimal Clinically Important DifferenceAdolescentAdultCohort StudiesDisability EvaluationFemaleHumansMalePain MeasurementYoung Adultclinical assessmentfemoroacetabular impingementgrading scalehipphysical therapyrehabilitation

Identifiers

PMID40123108
PMCPMC12481180

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.