Evidence map›Paper›PMID 40123015›Full record

ArticleInternational urology and nephrology2025

Safety and efficacy of WVTT (Rezum) in young men: preliminary data.

Antonio Minore, Loris Cacciatore, Giovanni Ferrari, Giampaolo Siena, Raffaele Balsamo, Simone Morselli, Roberto Castellucci, Francesco Varvello, Luca Cindolo

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonio MinoreDepartment of Urology, Fondazione Policlinico Campus Bio Medico di Roma, Via Alvaro Del Portillo 200, 00128, Rome, Italy. antonio.minore@gmail.com.
Loris CacciatoreDepartment of Urology, Fondazione Policlinico Campus Bio Medico di Roma, Via Alvaro Del Portillo 200, 00128, Rome, Italy.
Giovanni FerrariDepartment of Urology, C.Ur.E., Hesperia Hospital, Modena, Italy.
Giampaolo SienaDepartment of Experimental and Clinical Medicine - Unit of Oncologic Minimally-Invasive Urology and Andrology, University of Florence, Florence, Italy.
Raffaele BalsamoDepartment of Urology, AORN Ospedali dei Colli-Monaldi Hospital, Naples, Italy.
Simone MorselliDepartment of Urology, C.Ur.E., Hesperia Hospital, Modena, Italy.
Roberto CastellucciDepartment of Urology, C.Ur.E., Centro Urologico Europeo, Modena, Italy.
Francesco VarvelloDepartment of Urology, Michele e Pietro Ferrero Hospital, Alba-Bra, Italy.
Luca CindoloDepartment of Urology, C.Ur.E., Centro Urologico Europeo, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWater vapor thermal therapy (WVTT) is one of the latest developed minimally invasive surgical treatments (MIST) for benign prostatic hyperplasia-related symptoms (LUTS/BPH). We focused on the functional outcomes of patients < 50 years treated with Rezūm for BPH.

methodsWe prospectively recorded data on patients treated with Rezūm at 5 institutions from April 2020 to June 2021. Uroflowmetry, prostatic specific antigen (PSA), ultrasonography assessing prostate volume and post voiding residual volume (PVR), the International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF-5), and the question yes/no assessing ejaculatory dysfunction were recorded at baseline, and 3, 6 and 12 months later.

resultsTen patients were enrolled. The median operative time was 9 (IQR 8.25-13) min. All patients were dismissed a few hours after surgery with an indwelling urinary catheter that was removed after a median of 7 days (IQR 7-7). Each patient experienced an improvement both in terms of IPSS domain and in terms of maximal flow (Qmax) and PVR with a significative difference from the baseline observed at 3 months, stable until the last follow-up. Everyone maintained or gained antegrade ejaculation. No major post-operative complications were recorded, as just one patients experienced acute urinary retention after catheter removal.

conclusionsWVTT treatment is a feasible and safe minimally invasive option for patients < 50 y old with LUTS/BPH and showed optimal early functional outcomes.

Indexed as

Lower Urinary Tract SymptomsProstatic HyperplasiaSteamAdultHumansMaleMiddle AgedProspective StudiesTreatment OutcomeSteamBenign prostatic hyperplasiaLower urinary tract symptomsMinimally invasive surgical treatmentsMISTSurgical managementWater vapor thermal therapy

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.