Evidence map›Paper›PMID 40122984›Full record

SynthesisScientific reports2025

Differences in the rates of seroma complications between hernial sac transection and reduction after laparoscopic inguinal hernia repair: systematic review and meta-analysis.

Chairat Supsamutchai, Ratanakiat Pongratanakul, Jakrapan Jirasiritham, Puvee Punmeechao, Napaphat Poprom, Jarinya Wilasrusmee, Theejutha Meakleartmongkol, Settanan Plangsiri, Chumpon Wilasrusmee

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chairat SupsamutchaiDepartment of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Ratanakiat PongratanakulDepartment of Surgery, Fort Surasi Hospital, Siriraj , Thailand.
Jakrapan JirasirithamDepartment of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Puvee PunmeechaoDepartment of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Napaphat PopromDepartment of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Jarinya WilasrusmeeCollege of Medicine, Rangsit University, Bangkok, Thailand.
Theejutha MeakleartmongkolFaculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Settanan PlangsiriFaculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Chumpon WilasrusmeeDepartment of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. chumpon.wil@mahidol.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seroma formation is one of the most common postoperative complications after laparoscopic inguinal hernia repair (LIHR). Many techniques to reduce the incidence of seroma formation after LIHR have been described; however, the evidence for performing hernial sac transection (HST) technique is limited. Therefore, this study was conceived to evaluate the effect of HST on LIHR. We conducted a systematic review and meta-analysis of comparative studies according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) 2020. The PubMed, Embase, Springer, and the Cochrane databases were searched for relevant publications up to December 2023. Studies concerning laparoscopic inguinal hernia repair with clearly specified surgical techniques were included. Studies were excluded if they were open procedures or non-inguinal hernia repair. Egger's test and funnel plot analysis was used to assess bias. Outcomes were reported as odds ratio for dichotomous outcomes and as confidence intervals for continuous outcomes. No funding was received for this study. The study protocol was registered in PROSPERO under the number ID: CRD.42,024,530,115. A total of 3,076 patients in 9 studies were included in the analysis (4 RCTs, 4 retrospective cohorts, and 1 prospective cohort). Three, four, and two studies evaluated TEP, TAAP, and both techniques, respectively. The rate of seroma in HST transection was 57% lower than that in the reduction method (p value < 0.01), with low evidence of publication bias (Egger test and funnel plots, coefficient, 0.470; SE, 0.722; p = 0.275). In the subgroup analysis, 3 RCTs reported lower rates of seroma formation in HST (RR, 0.57; 95% CI, -0.24, 1.37), but the difference was not statistically significant. The rate of seroma formation in the HST for the TAPP method was significantly lower than that for the reduction method by approximately 53% (p value = 0.03). Compared with complete sac reduction, HST is associated with a lower seroma rate after LIHR.

Indexed as

Hernia, InguinalHerniorrhaphyLaparoscopyPostoperative ComplicationsSeromaHumans

Identifiers

PMID40122984
PMCPMC11930968

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.