ArticleMikrochimica acta2025
Trimetallic PtPdCo nanoalloy on hollow porous N-doped carbon fibers: A high-performance electrochemical immunosensor for procalcitonin detection in SIRS diagnosis.
Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Influence of CeOACS omega · 2025Article
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7 authors.
Funding
Abstract
Systemic inflammatory response syndrome (SIRS) poses a serious threat that influences patient survival and life quality. Its early and accurate diagnosis is paramount in clinics, where procalcitonin (PCT) is recognized as a key serological biomarker. Herein, well-dispersed PtPdCo nanoalloy was efficiently anchored on hollow porous N-doped carbon fibers (termed PtPdCo HPCNFs) through a sequential process involving electrospinning, pyrolysis, etching, and co-reduction. The morphology, structure, and physicochemical properties of PtPdCo HPCNFs were characterized by a set of techniques. Subsequently, the synthesized PtPdCo HPCNF nanocomposite was applied to build a label-free electrochemical amperometric immunosensor for ultrasensitive detection of PCT. Its performance was evaluated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). Notably, the biosensor demonstrated a wide dynamic linear range (0.0001-1000 ng mL
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