Evidence map›Paper›PMID 40122943›Full record

ArticlePediatric nephrology (Berlin, Germany)2025

Interval healthcare provider contact and blood pressure control in children with chronic kidney disease and hypertension.

John H Hammond, Derek K Ng, Eliza D Blanchette, Joseph T Flynn, Mark M Mitsnefes, Susan L Furth, Bradley A Warady, Tammy M Brady, CKiD Study Investigators

Registry-linked trialAbstract read
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00327860 (Chronic Kidney Disease in Children Prospective Cohort Study), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00327860 recruitingnot on this map

Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

TypeobservationalSponsorJohns Hopkins Bloomberg School of Public HealthRan2003 to 2028Enrolled1,300ConditionsChronic Kidney Disease
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

John H HammondDivision of Pediatric Nephrology, Johns Hopkins Children's Center, Baltimore, MD, 21287, USA. jhammo30@jhmi.edu.ORCID http://orcid.org/0000-0002-6121-3291
Derek K NgDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Eliza D BlanchetteDivision of Pediatric Nephrology, Children's Hospital Colorado, Aurora, CO, USA.
Joseph T FlynnDivision of Nephrology, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, USA.
Mark M MitsnefesDivision of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Susan L FurthDivision of Pediatric Nephrology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Bradley A WaradyDivision of Pediatric Nephrology, Children's Mercy Kansas City, Kansas City, MO, USA.
Tammy M BradyDivision of Pediatric Nephrology, Johns Hopkins Children's Center, Baltimore, MD, 21287, USA.
CKiD Study Investigators

Funding

Chronic Kidney Disease in Children Study (C-Kid)U01DK066174 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SUSAN L. FURTH · 2003 to 2026
$25.1M
CKiD Cardiovascular Testing Travel SupplementU01DK066143 · NIDDK · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI Bradley Alan Warady · 2003 to 2026
$24.2M
The Kidney Disease in Children Data Management and Analysis Center (KIDMAC)U24DK066116 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI Derek K Ng · 2018 to 2026
$12.6M
RENAL DISEASE EPIDEMIOLOGY TRAINING GRANTT32DK007732 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CREWS, DEIDRA CANDICE · 1995 to 2024
$7.7M
The Central Biochemistry Laboratory for the Chronic Kidney Disease in Children Cohort (CKiD)U24DK137522 · NIDDK · UNIVERSITY OF MINNESOTA · PI Jesse C Seegmiller · 2023 to 2026
$1.3M
NIDDK NIH HHS T32DK00732NIDDK NIH HHS T32 DK007732NIDDK NIH HHS U01 DK066143NIDDK NIH HHS U01 DK066174NIDDK NIH HHS U24 DK066116NIDDK NIH HHS U24 DK137522
6 · The paper itself

Abstract

backgroundPrior studies in the CKiD (Chronic Kidney Disease in Children) cohort have shown poor blood pressure (BP) control over time. It is unclear whether the lack of BP control is associated with frequency of provider contact between annual study visits.

methodsSix hundred eighty-nine CKiD participants with elevated BP or self-reported history of hypertension contributed longitudinal annual data (2,916 total visits). Provider visits were categorized as any well or sick visit, excluding emergency department visits. Repeated measures logistic regression quantified the association between number of visits over the last year (categorized as 0, 1-2, 3-5, 6-10 or > 10 visits) and BP control (defined as non-elevated BP at an annual CKiD visit). Models were unadjusted, minimally adjusted (controlling for sociodemographic factors), and fully adjusted (additionally controlling for chronic kidney disease (CKD) severity).

resultsCompared to those with no interval healthcare provider visits over the prior year, participants with 3-5 visits had significantly greater odds of BP control across all models (unadjusted, OR 1.45, 95% CI 1.10-1.89; minimally adjusted, OR 1.36, 95% CI 1.03-1.79; fully adjusted, OR 1.36, 95% CI 1.01-1.81); those with fewer or more frequent visits did not consistently have significant improvement in BP control.

conclusionsIn this cohort of youth with CKD and elevated BP, interval healthcare provider contact of 3-5 visits per year between annual CKiD visits was associated with improved BP control; less and more frequent contact was not, even after adjusting for CKD severity. Optimal frequency of health visits by CKD and comorbidity severity deserves further study.

Indexed as

Antihypertensive AgentsHypertensionRenal Insufficiency, ChronicAdolescentBlood PressureChildFemaleHumansLongitudinal StudiesMaleAntihypertensive AgentsAdherenceAdolescentCardiovascular diseasePediatricPreventionSecondary hypertensionYouth

Identifiers

PMID40122943
PMCPMC12187545

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.