ArticleAnnals of African medicine2025
Comparative Study of Conventional Opioid-based Anesthesia and Opioid-sparing Anesthesia in Patients Undergoing Laparoscopic Surgeries.
Article in Annals of African medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOpioid-sparing anesthesia (OSA) is an emerging concept in an attempt to overcome the potential side effects during postoperative recovery associated with opioid-based anesthesia. However, there is a need to assess the extent of pain control and side effects between the two. The objective of the study was to evaluate and compare intraoperative hemodynamic parameters, and postoperative pain control with a secondary objective to determine the postoperative nausea vomiting, and patient satisfaction levels postlaparoscopic surgery. METHODOLOGY: Eighty patients with ASA physical statuses 1 and 2 who were scheduled for laparoscopic procedures, ranging in age from 20 to 70, participated in the study. They were categorized into opioid group ( n = 40) and opioid sparing group ( n = 40). Participants in the opioid group provided general anesthesia with fentanyl and participants in the opioid-sparing group received general anesthesia without fentanyl but got an infusion after receiving a loading dose of dexmedetomidine. Assessing pain scores and hemodynamic parameters were the primary objective while postoperative nausea and vomiting (PONV) and patient satisfaction were the secondary objective.
resultsThe systolic blood pressure and diastolic blood pressure intraoperative hemodynamic parameters were comparable, with the exception of the heart rate, which was considerably greater in the opioid-sparing group at baseline, at 6 h, and 24 h ( P = 0.001). Up to 2 h, the opioid-sparing group's visual analog scale scores were considerably lower ( P = 0.001), and their patient satisfaction levels were higher ( P = 0.01). In both groups, the incidence of PONV was similar.
conclusionOSA can be used as an effective alternative to opioid anesthesia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.