Evidence map›Paper›PMID 40122139›Full record

ArticleThe Journal of small animal practice2025

Canine bilateral zygomatic sialadenitis: 20 cases (2000-2019).

A E Enache, S Maini, M Pivetta, E Jeanes, L Fleming, C Hartley, R Tetas Pont

Abstract read
In one paragraph

Article in The Journal of small animal practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A E EnacheNorth Downs Specialist Referrals, Bletchingley, UK.ORCID 0000-0002-1739-8989
S MainiDepartment of Clinical Sciences and Services, Queen Mother Hospital for Animals, Royal Veterinary College (RVC), London, UK.
M PivettaAntech Imaging Services, Irvine, California, USA.
E JeanesNorth Downs Specialist Referrals, Bletchingley, UK.
L FlemingDick White Referrals, Station Farm, Six Mile Bottom, UK.
C HartleyRoyal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-1246-6479
R Tetas PontDepartment of Clinical Sciences and Services, Queen Mother Hospital for Animals, Royal Veterinary College (RVC), London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe clinical findings, cross-sectional imaging features, management and outcome of dogs with bilateral zygomatic sialadenitis. MATERIALS AND

methodsClinical databases of three referral institutions were searched for dogs diagnosed with bilateral zygomatic sialadenitis who underwent magnetic resonance imaging or computed tomography of the head. Signalment, history, clinical, laboratory and imaging findings were reviewed.

resultsTwenty dogs with a mean age (±SD) of 7.1 (±2.7) years were included; Labradors were overrepresented (10/20). Common clinical signs included pain on opening the mouth (18/20), conjunctival hyperaemia (16/20), exophthalmos (15/20), periorbital pain (15/20), third eyelid protrusion (11/20) and resistance to retropulsion of the globes (11/20). Fifteen of twenty dogs had at least one concurrent systemic disease: skin allergy (5/15), hypertension (3/15), gastrointestinal (3/15), kidney (3/15), neurological (3/15) and periodontal disease (2/15), pancreatitis (2/15) and neoplasia (2/15). Neutrophilia (9/18) and leukocytosis (7/18) were the most common haematological abnormalities. When performed (11/20), aspiration cytology revealed predominantly degenerate neutrophils (9/11) and only 2/9 culture samples yielded bacterial growth. The zygomatic glands were predominantly hyperintense on both T1 and T2-weighted images (22/24) and symmetrically enlarged (20/24) with marked and heterogeneous contrast enhancement (18/24). In the computed tomography studies, the zygomatic glands were all hyperattenuating and contrast enhancing. Treatment included systemic antimicrobial (18/20), anti-inflammatory (14/20) and supportive treatment (16/20). Clinical signs improved in 16/20 dogs; however, 4/20 dogs were euthanised due to severe systemic disease. CLINICAL SIGNIFICANCE: Bilateral zygomatic sialadenitis is frequently associated with systemic disease in dogs. Clinical signs generally improve with systemic antimicrobial, anti-inflammatory and supportive treatment.

Indexed as

Dog DiseasesSialadenitisAnimalsAnti-Bacterial AgentsDogsFemaleMagnetic Resonance ImagingMaleRetrospective StudiesTomography, X-Ray ComputedZygomaAnti-Bacterial Agents

Identifiers

PMID40122139
PMCPMC12167697

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.