ArticleFuture medicinal chemistry2025
Zn (II) complex with vanillin derived Schiff base: antifungal, antibacterial, antioxidant and anticholinesterase activities.
Article in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Mono- and dinuclear thiophene-based palladium(ii) complexes bearing phosphorus ylides: synthesis, catalytic activity, cytotoxicity and molecular docking studies.RSC advances · 2026Article
- Antifungal Activity and Possible Mechanism of Action of the Zn (II) Complex With a Schiff Base Against Fluconazole-Resistant Strains of Candida spp. and Cryptococcus neoformans.Chemistry & biodiversity · 2026Article
- Synthesis and characterization of a new N4-Schiff base its zinc halide/pseudohalide complexes with thermal, antimicrobial, antioxidant, anticancer, DNA cleavage and wound healing properties.Scientific reports · 2026Article
- Metal-based triazoles as a medical marvel of the modern era: a comprehensive review.RSC advances · 2026Review
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo synthesize and characterize a Schiff base derived from vanillin and tris(hydroxymethyl)aminomethane (VTRIS) and the Zinc (II) complex [Zn(VTRIS) MATERIALS AND
methodsVTRIS and the Zn (II) complex were synthesized through condensation and complexation reactions, respectively. Structures were confirmed by electron spectroscopy in the UV-Vis, FT-IR and NMR regions. Toxicity was evaluated in Artemia salina, antimicrobial activity was evaluated by microdilution assay, ABTS and DPPH methods were used for antioxidant effect and the anticholinesterase potential was investigated.
resultsVTRIS and the complex showed low toxicity in
conclusionZn complexation potentiates VTRIS, and this compound exhibits promising antimicrobial, antioxidant, and anticholinesterase activities at nontoxic concentrations.
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Registered trials
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