Evidence map›Paper›PMID 40121688›Full record

SynthesisMedicina oral, patologia oral y cirugia bucal2025

Assessment of the prevalence of Behcet's disease in recurrent aphthous ulceration worldwide: a systematic review.

A-B Azevêdo, A-P Sobral, C-A Faria, J-S Sousa, W-R Silva, M-M Silveira

Abstract readSystematic Review
In one paragraph

Synthesis in Medicina oral, patologia oral y cirugia bucal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A-B AzevêdoPostgraduate Program in Dentistry School of Dentistry, University of Pernambuco R. Arnóbio Marques, 310, 50100-130, Recife, Pernambuco, Brazil weslay.rodriguess@upe.br.
A-P Sobral
C-A Faria
J-S Sousa
W-R Silva
M-M Silveira

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate the prevalence of Behcet's syndrome in patients with recurrent aphthous stomatitis (RAS). MATERIAL AND

methodsA search was performed in Scopus, Medline/PubMed, The Cochrane Library and Web of Science databases, according to PRISMA. In addition, a search was carried out in the DANS Easy Archive to access gray literature and a manual search in the reference list of included studies was used as an additional resource to refine the search. Cross-sectional studies in patients with recurrent aphthous stomatitis evaluating the diagnosis of Behcet's syndrome were analyzed to identify prevalence. The Joanna Briggs Institute (JBI) Critical Appraisal Checklist was used to assess the methodological quality of the articles.

resultsThe study design, sample size, sex, International Study Group (ISG) diagnostic criteria and prevalence of the syndrome were evaluated. After screening and reading the articles in full, 7 met the inclusion criteria. The articles involved a total of 2841 participants with recurrent aphthous ulcerations, with 141 having a diagnosis of Behcet's syndrome. Studies were of good quality as assessed by the JBI Critical Appraisal Checklist for cross-sectional studies.

conclusionsThe prevalence of Behcet's syndrome in patients with recurrent aphthous stomatitis (RAS) is generally low, with similar frequency in both sexes and more common in the range of countries that extends from the Mediterranean Basin to the Far East.

Indexed as

Behcet SyndromeStomatitis, AphthousGlobal HealthHumansPrevalenceRecurrence

Identifiers

PMID40121688
PMCPMC12221144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.