Evidence map›Paper›PMID 40121677›Full record

ReviewMedicina oral, patologia oral y cirugia bucal2025

Oral leukoplakia: still an enigmatic disorder.

J-M Aguirre-Urizar

Abstract readReview
In one paragraph

Review in Medicina oral, patologia oral y cirugia bucal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

J-M Aguirre-UrizarDepartment of Stomatology. Faculty of Medicine and Nursing University of the Basque Country/EHU Barrio Sarriena s/n. 48940 Leioa. Bizkaia. Spain josemanuel.aguirre@ehu-eus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral leukoplakia is the most frequent and representative potentially malignant disorder of what is known as oral precancer. Since the first descriptions, this pathology, which initially seems simple, has been the subject of controversy and discussion, and it still maintains multiple unknowns and enigmas to be solved. MATERIAL AND

methodsA narrative and integrative review of the epidemiological, pathogenetic, diagnostic, prognostic and therapeutic aspects of this important oral disorder has been carried out.

resultsOral leukoplakia still presents multiple enigmas regarding its actual epidemiology, its multifactorial and multistage pathogenesis, its definition and diagnosis, its malignant development and its treatment.

conclusionsWe must conduct well-designed prospective studies on this fascinating oral pathology, on well-diagnosed clinical cases with clinicopathological criteria agreed and accepted by the scientific community. Only in this way will we be able to clarify the enigmas it still presents.

Indexed as

Leukoplakia, OralHumans

Identifiers

PMID40121677
PMCPMC12395576

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.