SynthesisArchives of dermatological research2025
Kyrle disease: a systematic review of clinical features, diagnostic approaches, dermatoscopic insights, systemic associations, and therapeutic strategies.
Synthesis in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Successful Trifarotene Treatment of a Typical Kyrle's Disease With Overview of Topical Therapies.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026Article
- Dermoscopy of Acquired Perforating Dermatoses: A Case Series and Review of the Literature.Life (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kyrle disease (KD) is a rare dermatologic condition characterized by hyperkeratotic papules with central keratotic plugs, often associated with systemic conditions such as diabetes and chronic kidney disease. Due to its clinical overlap with other dermatologic disorders, KD is frequently misdiagnosed. Diagnosis primarily relies on characteristic histopathological findings, with dermoscopy serving as a valuable adjunct for clinical assessment. This systematic review highlights KD's clinical features, systemic associations, dermoscopy findings, differential diagnosis, and current treatment approaches. While some therapies have shown promise, the lack of standardized management underscores the need for further research. By consolidating the existing literature, this systematic review emphasizes the importance of a multidisciplinary approach in managing KD and calls for future studies to establish standardized diagnostic and therapeutic protocols to improve patient outcomes.
Indexed as
Identifiers
40121580What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.