ArticleBMC psychiatry2025
The impact of cognitive behavioral therapy on disease uncertainty, stressful life events, quality of life, anxiety, and depression in glioma patients undergoing chemotherapy: a quasi-experimental study.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- From diagnosis to daily realities: longitudinal phenomenological exploration of symptom trajectories in glioma survivorship.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Suicide Risk in Glioblastoma Multiforme: A Brief Review of Risk Factors, Screening, and Prevention.Current psychiatry reports · 2026Review
- Development and Validation of a Machine Learning-Based Prediction Model for Illness Uncertainty in Patients with Malignant Tumors.Healthcare (Basel, Switzerland) · 2026Article
- Dyadic Coping and Illness Uncertainty in Cancer Patient-Caregiver Dyads: Interactive Mechanisms, Heterogeneity, and Integrated Intervention Directions-A Narrative Review (2021-2025).Healthcare (Basel, Switzerland) · 2026Review
- Symptoms experienced during the first 4 months of chemotherapy administration: a longitudinal cohort study in an Australian cancer treatment unit.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Evidence-Based Strategies for Addressing Cancer- and Treatment-Related Cognitive Impairment: A Review.Biomolecules & therapeutics · 2026Review
- The relationship between illness uncertainty and preoperative anxiety in surgical patients: the moderating role of mental health literacy.Frontiers in psychology · 2026Article
- Impact of hospice care plus estazolam on sleep and psychological distress in advanced gastrointestinal cancer: a real-world observational study.Frontiers in medicine · 2026Article
- Efficacy of hybrid remote neuropsychological rehabilitation on cognitive complaints in post-therapeutic lower-grade glioma: the FREEDOME randomized study protocol.Frontiers in psychology · 2025Article
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Authors and funding
8 authors.
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Abstract
objectiveTo investigate the effect of cognitive behavioral therapy on disease uncertainty and stressful life events in glioma patients undergoing chemotherapy.
methodsThis quasi-experimental study enrolled 90 glioma patients from Sanmenxia Central Hospital between January and December 2021. Patients were divided into an intervention group (n = 45) or a control group (n = 45). The intervention group received cognitive behavioral therapy provided by nurses, while the control group received routine nursing care. Pre- and post-intervention assessments were conducted using the Mishel uncertainty in illness scale (MUIS), life events scale (LES), self-rating anxiety scale (SAS), self-rating depression scale (SDS), and quality of life scale (WHOQOL-BREF).
resultsAfter four cycles of chemotherapy, the study group demonstrated a statistically significant decrease in MUIS and LES scores compared to the control group (p < 0.05). The study group showed significantly lower SAS and SDS scores than the control group (p < 0.05). Finally, the study group reported significantly higher WHOQOL-BREF scores than the control group (p < 0.05).
conclusionThe study revealed that the group that received CBT showed significant improvements in the psychological well-being of glioma patients undergoing chemotherapy. These findings suggest that incorporating CBT into standard nursing care can effectively improve the psychological well-being and quality of life of glioma patients during chemotherapy.
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