Evidence map›Paper›PMID 40121342›Full record

ArticleNeuroscience bulletin2025

Mapping Brain-Wide Neural Activity of Murine Attentional Processing in the Five-Choice Serial Reaction Time Task.

Yin Yue, Youming Tan, Pin Yang, Shu Zhang, Hongzhen Pan, Yiran Lang, Zengqiang Yuan

Abstract read
In one paragraph

Article in Neuroscience bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yin YueThe Brain Science Center, Beijing Institute of Basic Medical Sciences, Beijing, 100850, China. yuey17@tsinghua.org.cn.ORCID http://orcid.org/0009-0009-7470-3175
Youming TanHengyang Medical School, University of South China, Hengyang, 421001, China.
Pin YangSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230022, China.
Shu ZhangSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230022, China.
Hongzhen PanSchool of Medical Technology, Beijing Institute of Technology, Beijing, 100081, China.
Yiran LangSchool of Medical Technology, Beijing Institute of Technology, Beijing, 100081, China. yiran.lang@bit.edu.cn.ORCID http://orcid.org/0000-0001-8134-1162
Zengqiang YuanThe Brain Science Center, Beijing Institute of Basic Medical Sciences, Beijing, 100850, China. zqyuan@bmi.ac.cn.ORCID http://orcid.org/0000-0001-5739-2867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention is the cornerstone of effective functioning in a complex and information-rich world. While the neural activity of attention has been extensively studied in the cortex, the brain-wide neural activity patterns are largely unknown. In this study, we conducted a comprehensive analysis of neural activity across the mouse brain during attentional processing using EEG and c-Fos staining, utilizing hierarchical clustering and c-Fos-based functional network analysis to evaluate the c-Fos activation patterns. Our findings reveal that a wide range of brain regions are activated, notably in the high-order cortex, thalamus, and brain stem regions involved in advanced cognition and arousal regulation, with the central lateral nucleus of the thalamus as a strong hub, suggesting the crucial role of the thalamus in attention control. These results provide valuable insights into the neural network mechanisms underlying attention, offering a foundation for formulating functional hypotheses and conducting circuit-level testing.

Indexed as

AttentionBrainBrain MappingChoice BehaviorReaction TimeAnimalsElectroencephalographyMaleMiceMice, Inbred C57BLProto-Oncogene Proteins c-fosProto-Oncogene Proteins c-fos5-CSRTTAttentionc-FosEEGFunctional network

Identifiers

PMID40121342
PMCPMC12014984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.