Evidence map›Paper›PMID 40120996›Full record

ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2025

Comparison of the prognostic value of right atrial echocardiographic parameters in pulmonary arterial hypertension.

Danny Mohama, Pitchaya Worapongsatitaya, Bettia Celestin, Felipe Kazmirczak, Shadi P Bagherzadeh, Kurt W Prins, Sasha Z Prisco, E Kenneth Weir, Roham Zamanian, Francois Haddad and 1 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Danny MohamaCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
Pitchaya WorapongsatitayaCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
Bettia CelestinCardiovascular Division, Department of Medicine, Stanford University, Palo Alto, California.
Felipe KazmirczakCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
Shadi P BagherzadehCardiovascular Division, Department of Medicine, Stanford University, Palo Alto, California.
Kurt W PrinsCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
Sasha Z PriscoCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
E Kenneth WeirCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
Roham ZamanianDivision of Pulmonary and Critical Care, Department of Medicine, Stanford University, Palo Alto, California.
Francois HaddadCardiovascular Division, Department of Medicine, Stanford University, Palo Alto, California. Electronic address: fhaddad@stanford.edu.
Thenappan ThenappanCardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota. Electronic address: tthenapp@umn.edu.

Funding

GP130 Antagonism in Porcine RV Pressure OverloadR01HL162927 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$3.3M
Multi-scale Investigation of Sex Differences in Right Ventricular Function via Estrogen-Microtubule InteractionsR01HL158795 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$2.8M
Modulating the Microbiome to Enhance Right Ventricular Function in Pulmonary Arterial HypertensionK08HL168166 · NHLBI · UNIVERSITY OF MINNESOTA · PI Sasha Zheng Prisco · 2024 to 2026
$525k
NHLBI NIH HHS K08 HL168166NHLBI NIH HHS R01 HL158795NHLBI NIH HHS R01 HL162927
6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) guidelines advocate measures of area for right atrial (RA) dimensions, while echocardiographic guidelines recommend RA volume. We compared the prognostic value of RA echocardiographic parameters to predict transplant-free survival in 332 adult patients with PAH. RA area correlated strongly with volume (r = 0.96). After adjusting for age and sex, for every 1-standardized unit increase in RA area index, volume index, and major axis dimension, there were 21%, 18%, and 18% higher hazards of mortality or transplant, respectively. However, no RA parameter was independently associated with transplant-free survival when adjusted for Registry to Evaluate Early and Long-Term PAH Disease Management lite score. RA area index had the highest area under the curve for predicting transplant-free survival.

Indexed as

EchocardiographyHeart AtriaHypertension, PulmonaryAdultFemaleHumansMaleMiddle AgedPrognosisPulmonary Arterial HypertensionRetrospective Studiesareapulmonary hypertensionright ventriclesurvivalvolume

Identifiers

PMID40120996
PMCPMC12695458

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.