Evidence map›Paper›PMID 40120812›Full record

ArticleJournal of substance use and addiction treatment2025

Prenatal opioid use disorder and child protective service involvement: Does consistent treatment matter?

Yi Wang, Deborah Ehrenthal, Ai Bo, Lawrence Berger

Abstract read
In one paragraph

Article in Journal of substance use and addiction treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi WangSilberman School of Social Work, Hunter College, City University of New York, New York City, NY, United States of America; Social Science Research Institute, The Pennsylvania State University, University Park, PA, United States of America. Electronic address: yw1279@hunter.cuny.edu.
Deborah EhrenthalSocial Science Research Institute, The Pennsylvania State University, University Park, PA, United States of America; Department of Biobehavioral Health, College of Health and Human Development, The Pennsylvania State University, University Park, PA, United States of America.
Ai BoCollege of Community Engagement and Professions, Helen Bader School of Social Welfare, Department of Social Work, University of Wisconsin-Milwaukee, WI, United States of America.
Lawrence BergerSandra Rosenbaum School of Social Work and Institute for Research on Poverty, University of Wisconsin-Madison, WI, United States of America.

Funding

Prenatal Opioid Exposure: Birth, health, socioeconomic, and educational outcomes of mothers and their childrenR01HD102125 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI BERGER, LAWRENCE M, EHRENTHAL, DEBORAH BETH · 2020 to 2024
$2.2M
NICHD NIH HHS R01 HD102125
6 · The paper itself

Abstract

backgroundInfants born to individuals with opioid use disorder (OUD) often face greater scrutiny from child protective services (CPS), particularly in states like Wisconsin that mandate reporting for prenatal substance exposure. While consistent medication for opioid use disorder (MOUD) is recommended to stabilize the prenatal environment, such mandatory reporting policies may discourage seeking treatment.

methodsThis research used Wisconsin's linked administrative data to estimate associations between prenatal OUD diagnosis and CPS involvement, focusing on variation therein by MOUD treatment consistency.

resultsOf the 258,828 Medicaid-covered singleton births from 2010 to 2019, 6091 (2.4 %) were to individuals with OUD. Among these, 2349 (38.6 %) received high consistency treatment (defined as receiving MOUD for 5 or more consecutive months before the birth), 701 (11.5 %) had moderate consistency treatment (2-4 consecutive months), 660 (10.8 %) underwent intermittent treatment (<2 consecutive months), and 2381 (39.1 %) were untreated. Logistic regressions show that OUD diagnosis was associated with elevated risk of CPS referrals and removals within 30 days post-birth. The presence of other co-occurring substance use and mental health disorders was associated with additional increases in these risks. Though individuals receiving MOUD treatment had higher referral risk compared to untreated, those who received moderately and highly consistent treatment faced lower removal risk relative to those with intermittent treatment. Notably, the high consistency treatment group exhibited the lowest referral and removal rates across all treatment groups.

conclusionThese findings underscore the need to promote high consistency MOUD treatment among pregnant individuals with OUD by clarifying its benefits and mitigating concerns regarding CPS involvement.

Indexed as

Child Protective ServicesOpiate Substitution TreatmentOpioid-Related DisordersPregnancy ComplicationsPrenatal Exposure Delayed EffectsAdultFemaleHumansInfantInfant, NewbornMaleMedicaidPregnancyUnited StatesWisconsinYoung AdultChild protective servicesMedications for opioid use disorderOpioid use disorderPregnancy

Identifiers

PMID40120812
PMCPMC12043111

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.