ReviewBiological psychiatry2026
Deep Brain Stimulation Response Circuits in Obsessive-Compulsive Disorder.
Review in Biological psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Next-Generation Neuromodulation for Anxiety: Circuit-Based and Personalized Approaches.Current psychiatry reports · 2026Review
- Efficacy of Dextromethorphan Augmentation in SSRI-Resistant Obsessive-Compulsive Disorder: A Randomized Controlled Trial.Health science reports · 2026Article
- Pallidal alpha activity is an electrophysiological biomarker of symptom severity in obsessive-compulsive disorder.Research square · 2026Article
- Human orbitofrontal neural activity is linked to obsessive-compulsive behavioral dynamics.Cell · 2026Article
- Translational prospectives for deep brain stimulation and low-intensity focused ultrasound neuromodulation: IFCN Handbook chapter.Clinical neurophysiology practice · 2026Review
- Fronto-cingulate gamma synchrony predicts deep brain stimulation response in treatment-resistant depression: preliminary evidence.Journal of psychiatry & neuroscience : JPN · 2026Article
- A Multi-Symptom Circuit Architecture of Obsessive-Compulsive Disorder.medRxiv : the preprint server for health sciences · 2025Article
- Neuroimaging and Machine Learning in OCD: Advances in Diagnostic and Therapeutic Insights.Brain sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
In the field of deep brain stimulation (DBS), 2 major themes are currently making significant progress. The first of these is the framework of connectomic DBS, in which circuits that are associated with improvements of specific symptoms are described and targeted to improve and potentially personalize treatment. The second theme is related to the concept of brain sensing and adaptive DBS, which are aimed at identifying neural biomarkers that may guide stimulation in a closed-loop fashion. In DBS for obsessive-compulsive disorder (OCD), substantial progress has been made on both ends over the last 5 years. Together, the results have begun to draw a picture of exactly which circuit is associated with treatment response and how it may be affected by dysfunctional brain activity that may be attenuated using DBS. This knowledge, if further refined and validated, will define where, when, and how to stimulate which patients with OCD. We review the key studies from recent years with the aim of aggregating and condensing findings along both spatial and temporal domains. The result is a concept that anatomically defines a circuit that is likely dysfunctional in patients with typical OCD phenotypes and that may be adaptively targeted using DBS to maximally improve symptoms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.