Evidence map›Paper›PMID 40120325›Full record

ArticleInternational journal of surgery case reports2025

Colic ameboma mimicking colic cancer: A case report.

Tayssir Khlif, Salsabil Nasri, Amine Ben Safta, Farah Hamza, Wided Ajouli, Ramzi Nouira

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tayssir KhlifDepartment B of Digestive Surgery, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia. Electronic address: Tayssirkhlif@gmail.com.
Salsabil NasriDepartment B of Digestive Surgery, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia.
Amine Ben SaftaDepartment B of Digestive Surgery, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia.
Farah HamzaDepartment of Radiology, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia.
Wided AjouliDepartment of Anatomical Pathology, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia.
Ramzi NouiraDepartment B of Digestive Surgery, Charles Nicolle University Hospital, University of Medecine of Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAmoebic colitis, caused by the protozoan Entamoeba histolytica, is a significant global health concern, ranking as the second leading cause of parasitic infection-related mortality. The disease manifests across a wide clinical spectrum, from asymptomatic carriers to severe necrotizing colitis. Rarely, it can form an inflammatory mass, or ameboma, which may mimic malignancy. CASE PRESENTATION: We report a case of a 60-year-old female presenting with acute right iliac pain, fever, and nausea, but no diarrhea or recent travel history. Imaging revealed irregular cecal thickening with features suggestive of a perilesional abscess. Exploratory laparotomy identified a 7 cm cecal mass with necrotic tissue, leading to a right hemicolectomy. Histopathology confirmed amoebic colitis with trophozoites in necrotic areas. Postoperative recovery was uneventful with antibiotic therapy. DISCUSSION: Ameboma, an uncommon complication of amoebic colitis, poses diagnostic challenges due to its tumor-like appearance. Misdiagnosis is common, especially in non-endemic regions, where clinical and radiological findings often mimic malignancy. Diagnosis requires a combination of serology, stool examination, and biopsy. Treatment is primarily medical, with surgical intervention reserved for complications. Preventive strategies, including sanitation improvements and vaccine development, are crucial to reducing disease burden.

conclusionThis case underscores the importance of considering amoebiasis in differential diagnoses, even in non-endemic regions. Enhanced diagnostic awareness and preventive measures can significantly improve outcomes and reduce the global health impact of amoebiasis.

Indexed as

AmebomaColonic neoplasmsDiagnosisDifferentialRare diseases

Identifiers

PMID40120325
PMCPMC11981754

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