Evidence map›Paper›PMID 40120083›Full record

ArticleEpilepsia open2025

Epilepsy syndromes classification.

Elaine C Wirrell, Nicola Specchio, Rima Nabbout, Phillip L Pearl, Kate Riney

Abstract read
In one paragraph

Article in Epilepsia open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elaine C WirrellDivisions of Neurology and Epilepsy, Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0003-3015-8282
Nicola SpecchioNeurology, Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital, Scientific Institute for Research and Health Care, Full Member of European Reference Network on Rare and Complex Epilepsies EpiCARE, Rome, Italy.ORCID https://orcid.org/0000-0002-8120-0287
Rima NabboutDepartment of Pediatric Neurology, Reference Center for Rare Epilepsies, Necker Enfants Malades, Assistance Publique Hôpitaux de Paris, Member of EpiCARE, Imagine Institute, National Institute of Health and Medical Research, Mixed Unit of Research 1163, University of Paris, Paris, France.ORCID https://orcid.org/0000-0001-5877-4074
Phillip L PearlDepartment of Neurology, Epilepsy and Clinical Neurophysiology, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-6373-1068
Kate RineyNeurosciences Unit, Queensland Children's Hospital, South Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-1122-3555

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with "a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings". Syndromes often present in an age-dependent manner, carry both prognostic and treatment implications, and are associated with a specific range of comorbidities. Syndromes are most commonly identified in young children and are less frequent in adults. Syndrome identification assists clinicians in selecting the highest yield investigations, the most effective therapies, and allows them to give more accurate prognoses both with regards to seizure control and potential remission as well as expected, associated comorbidities. This review outlines how syndromes are organized and defined, highlighting the characteristic features of the more common entities. PLAIN LANGUAGE SUMMARY: Epilepsy syndromes are identifiable entities that are characterized by specific seizure type(s) and EEG findings. Identification of an epilepsy syndrome often provides a clue to the underlying cause, helps clinicians select the most effective treatments, and provides information on the likely outcome.

Indexed as

EEGepilepsyepilepsy syndromeseizures

Identifiers

PMID40120083
PMCPMC13394629

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.