Evidence map›Paper›PMID 40120065›Full record

ArticleInsights into imaging2025

Generative pre-trained transformer 4o (GPT-4o) in solving text-based multiple response questions for European Diploma in Radiology (EDiR): a comparative study with radiologists.

Jakub Pristoupil, Laura Oleaga, Vanesa Junquero, Cristina Merino, Ozbek Suha Sureyya, Martin Kyncl, Andrea Burgetova, Lukas Lambert

Abstract read
In one paragraph

Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jakub PristoupilDepartment of Imaging Methods, Motol University Hospital and Second Faculty of Medicine, Charles University, Prague, Czech Republic.
Laura OleagaDepartment of Radiology, Clinical Diagnostic Imaging Centre, Hospital Clínic de Barcelona, Barcelona, Spain.
Vanesa JunqueroDepartment of Radiology, Clinical Diagnostic Imaging Centre, Hospital Clínic de Barcelona, Barcelona, Spain.
Cristina MerinoDepartment of Radiology, Clinical Diagnostic Imaging Centre, Hospital Clínic de Barcelona, Barcelona, Spain.
Ozbek Suha SureyyaEra Radiology Center, Izmir, Turkey.
Martin KynclDepartment of Imaging Methods, Motol University Hospital and Second Faculty of Medicine, Charles University, Prague, Czech Republic.
Andrea BurgetovaDepartment of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
Lukas LambertDepartment of Imaging Methods, Motol University Hospital and Second Faculty of Medicine, Charles University, Prague, Czech Republic. lambert.lukas@gmail.com.ORCID http://orcid.org/0000-0003-2299-4707

Funding

Charles University in Prague Cooperatio, Medical Diagnostics and Basic Medical SciencesMinisterstvo Zdravotnictví Ceské Republiky MH CZ-DRO, Motol University Hospital, 00064203 and General University Hospital in Prague, 00064165
6 · The paper itself

Abstract

objectivesThis study aims to assess the accuracy of generative pre-trained transformer 4o (GPT-4o) in answering multiple response questions from the European Diploma in Radiology (EDiR) examination, comparing its performance to that of human candidates. MATERIALS AND

methodsResults from 42 EDiR candidates across Europe were compared to those from 26 fourth-year medical students who answered exclusively using the ChatGPT-4o in a prospective study (October 2024). The challenge consisted of 52 recall or understanding-based EDiR multiple-response questions, all without visual inputs.

resultsThe GPT-4o achieved a mean score of 82.1 ± 3.0%, significantly outperforming the EDiR candidates with 49.4 ± 10.5% (p < 0.0001). In particular, chatGPT-4o demonstrated higher true positive rates while maintaining lower false positive rates compared to EDiR candidates, with a higher accuracy rate in all radiology subspecialties (p < 0.0001) except informatics (p = 0.20). There was near-perfect agreement between GPT-4 responses (κ = 0.872) and moderate agreement among EDiR participants (κ = 0.334). Exit surveys revealed that all participants used the copy-and-paste feature, and 73% submitted additional questions to clarify responses.

conclusionsGPT-4o significantly outperformed human candidates in low-order, text-based EDiR multiple-response questions, demonstrating higher accuracy and reliability. These results highlight GPT-4o's potential in answering text-based radiology questions. Further research is necessary to investigate its performance across different question formats and candidate populations to ensure broader applicability and reliability. CRITICAL RELEVANCE STATEMENT: GPT-4o significantly outperforms human candidates in factual radiology text-based questions in the EDiR, excelling especially in identifying correct responses, with a higher accuracy rate compared to radiologists. KEY POINTS: In EDiR text-based questions, ChatGPT-4o scored higher (82%) than EDiR participants (49%). Compared to radiologists, GPT-4o excelled in identifying correct responses. GPT-4o responses demonstrated higher agreement (κ = 0.87) compared to EDiR candidates (κ = 0.33).

Indexed as

Artificial intelligenceExaminationNatural language processingRadiology

Identifiers

PMID40120065
PMCPMC11929644

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.