Evidence map›Paper›PMID 40120015›Full record

Observational studyJournal of autism and developmental disorders2026

Prenatal Exposure to Ambient Particulate Matter and Autism Spectrum Disorder in Children, a Case Control Study in France.

Marion Mortamais, Jeanne Sandrine Ongono, Cécile Michelon, Ian Hough, Emie Seyve, Itai Kloog, Cécile Zaros, Marie-Aline Charles, Johanna Lepeule, Amaria Baghdadli

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of autism and developmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marion MortamaisInstitute for Neurosciences of Montpellier (INM), University of Montpellier, Inserm, Montpellier, France.ORCID http://orcid.org/0000-0003-3983-9826
Jeanne Sandrine OngonoCentre de Ressource Autisme Languedoc-Roussillon et Centre d'Excellence sur l'Autisme et les Troubles Neuro-développementaux (CeAND), 291 Avenue du Doyen Giraud, Montpellier, 34000, France.ORCID http://orcid.org/0000-0002-9883-2424
Cécile MichelonCentre de Ressource Autisme Languedoc-Roussillon et Centre d'Excellence sur l'Autisme et les Troubles Neuro-développementaux (CeAND), 291 Avenue du Doyen Giraud, Montpellier, 34000, France.ORCID http://orcid.org/0009-0008-3946-057X
Ian HoughUniversity Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology Applied to Development and Respiratory Health, IAB, Grenoble, France.ORCID http://orcid.org/0000-0001-7948-6995
Emie SeyveUniversity Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology Applied to Development and Respiratory Health, IAB, Grenoble, France.
Itai KloogDepartment of Geography and Environmental Development, Ben-Gurion University of the Negev, Be'er Sheva, Israel.ORCID http://orcid.org/0000-0003-1708-7440
Cécile ZarosFrench Institute for Demographic Studies (Ined), French Institute for Medical Research and Health (Inserm), French Blood Agency, ELFE Joint Unit, Paris, France.ORCID http://orcid.org/0000-0003-1711-4373
Marie-Aline CharlesFrench Institute for Demographic Studies (Ined), French Institute for Medical Research and Health (Inserm), French Blood Agency, ELFE Joint Unit, Paris, France.ORCID http://orcid.org/0000-0003-4025-4390
Johanna LepeuleUniversity Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology Applied to Development and Respiratory Health, IAB, Grenoble, France.ORCID http://orcid.org/0000-0001-8907-197X
Amaria BaghdadliCentre de Ressource Autisme Languedoc-Roussillon et Centre d'Excellence sur l'Autisme et les Troubles Neuro-développementaux (CeAND), 291 Avenue du Doyen Giraud, Montpellier, 34000, France. a-baghdadli@chu-montpellier.fr.ORCID http://orcid.org/0000-0002-5679-7544

Funding

Caisse nationale de solidarité pour l'autonomie 030319Centre Hospitalier Régional Universitaire de Montpellier AOIPHRCN 2013 13-0232
6 · The paper itself

Abstract

A series of epidemiological studies conducted in the United States have consistently shown an increased risk of autism spectrum disorder (ASD) in children associated with pre- and postnatal exposure to ambient particulate matter (PM). In Europe, studies are scarce and results are inconsistent. We aimed to investigate the association between prenatal exposure to PM and the risk of ASD in France. ASD cases were participants from the ELENA cohort. Controls children from the ELFE cohort were matched by sex, year (± 2) and region of birth. Prenatal exposures to PM10 and to PM2.5 were estimated between 2008 and 2013 using innovative hybrid spatio-temporal models developed for France. Conditional logistic regression models adjusted for birth season, parent's age at the child birth and parental education level were run. We included 125 ASD cases and 500 controls. Prenatal PM2.5 and PM10 median (IQR) concentration estimates were respectively 16.3 (3.9) µg/m

Indexed as

Autism Spectrum DisorderParticulate MatterPrenatal Exposure Delayed EffectsCase-Control StudiesChildChild, PreschoolFemaleFranceHumansMalePregnancyRisk FactorsParticulate MatterAir pollutionAutism spectrum disorderCase control studyEnvironmental risk factorParticulate matter

Identifiers

PMID40120015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.