ArticleInsights into imaging2025
Myocardial late enhancement using dual-source CT: intraindividual comparison of single-energy shuttle and dual-energy acquisition.
Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- CT-derived myocardial extracellular volume: current evidence, clinical utility, and the emerging role of photon-counting CT-a systematic review.European radiology experimental · 2026Pooled it
- Diagnostic Value and Operational Recommendations for Late Iodine Enhancement and ECV Quantification in Single-Energy Computed Tomography: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Image-quality optimization for late iodine enhancement with photon-counting CT: impact of spectral analysis and reconstruction parameters.La Radiologia medica · 2026Article
- Improved image quality and greater diagnostic suitability in myocardial delayed enhancement CT with deep learning image reconstruction.Japanese journal of radiology · 2026Article
- Impact of contrast medium volume on myocardial extracellular volume measurement accuracy in first-generation photon-counting detector CT.The international journal of cardiovascular imaging · 2026Article
- Myocardial characterization using late enhancement photon-counting detector CT in ventricular arrhythmia: comparison with electroanatomical mapping.Insights into imaging · 2025Article
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6 authors.
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Abstract
objectivesMyocardial computed tomography late enhancement (CT-LE) is a valuable modality used for the assessment of myocardial infarction and fibrosis and is effective in detecting latent cardiac amyloidosis. However, the optimal acquisition mode for CT-LE remains unknown. Here, we compared single-energy shuttle mode and DE mode for improving the quality of CT-LE imaging using dual-source CT.
methodsFifteen patients with suspected or known ischemic heart disease underwent CT-LE imaging 5 min after coronary CT in both shuttle and dual-energy (DE) modes. In DE mode, virtual monoenergetic images at various keVs were reconstructed, and extracellular volume (ECV) was quantified using iodine-specific images. For shuttle mode, ECV was assessed by subtracting the volume from pre-contrast images from CT-LE after non-rigid registration.
resultsIn DE mode, signal-noise-to-ratio was the highest at 70 keV, but it was still lower than that in shuttle mode (p < 0.001). Contrast-noise-to-ratio was the highest on DE mode at 40 keV and was comparable with that in shuttle mode (p = 0.51). Interobserver agreement for infarct detection was higher in shuttle mode (kappa = 0.981) compared to DE mode (kappa = 0.808). Global ECV was comparable between shuttle and DE modes (p = 0.96). However, the coefficient of variation of segmental ECV was significantly lower in shuttle mode (p < 0.001).
conclusionShuttle mode CT-LE demonstrates superior image quality, better agreement in infarct detection, and ECV consistency in comparison to DE mode, suggesting its potential as the preferred approach for CT-LE imaging using dual-source CT despite limited z-axis coverage of 10.5 cm. CLINICAL RELEVANCE STATEMENT: CT late enhancement imaging in shuttle mode provides superior image quality and consistent extracellular volume measurements compared to dual-energy mode, highlighting its potential as the preferred acquisition method for CT late enhancement imaging in dual-source CT. KEY POINTS: Shuttle mode and dual-energy acquisition are compared for optimal myocardial CT-late enhancement (CT-LE) imaging. Shuttle mode can provide better image quality and more consistent extracellular volume measurements. Despite limited coverage, shuttle mode may be preferred for myocardial CT-LE imaging.
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