ArticleInternational ophthalmology2025
Evaluation of the clinical management of Graves' Orbitopathy according to severity: a real-life Analysis.
Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
purposeDue to the clinical and prognostic implications of Graves' Orbitopathy (GO), clinical care needs to be tailored to current recommendations, but real-life information is scarce. We aim to describe GO management in a real-life setting for health care improvement.
methodsThis is a retrospective cohort study evaluating the clinical performance of clinicians attending patients diagnosed with GO. All cases with GO from 2018 to 2021 were included in the analysis, with no exclusion criteria. We performed an evaluation of the healthcare provided to these patients, with clinical performance evaluated from diagnostic and therapeutic viewpoints. A backwards stepwise multivariate binomial logistic regression analysis was run to assess the variables associated with severity.
resultsThis was a cohort of 151 cases, predominantly of women in the fifth decade of life, most of whom had hyperthyroidism. There were 50 (33.1%) cases with moderate-severe GO, but none of them with sight-threatening disease. Total annualized visits were more frequent to endocrinologists than ophthalmologists, except for moderate-severe cases. Active smoking (57 cases; 37.7%), unstable hyperthyroidism (59 cases; 39.1%), and elevated maximum TSI levels (136; 90.1%) conditioned clinical care. Altogether, the performance of an imaging technique, the use of systemic corticosteroid therapy and eyelid surgery were significantly different in those with more severe GO.
conclusionClinical care provided to patients with GO is variable and influenced by several variables. Both endocrinologists and ophthalmologists must coordinate to ensure a unified patient-tailored protocol that covers all these patients' needs.
Indexed as
Identifiers
40119963What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.