Evidence map›Paper›PMID 40119955›Full record

ArticleJournal of gastrointestinal cancer2025

Current Status of Gastrectomy for Gastric Cancer in Oldest-old Patients Aged 85 Years or Older.

Kazuaki Matsui, Yoshiki Kawaguchi, Takahiro Iwai, Yukiko Torizaki, Yoko Adachi, Hirofumi Shimoda, Takehiro Shimada, Yasuhito Sekimoto, Hidejiro Urakami, Shiko Seki

Abstract read
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In one paragraph

Article in Journal of gastrointestinal cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kazuaki MatsuiDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan. kazuaki.matsui11@gmail.com.
Yoshiki KawaguchiDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.
Takahiro IwaiDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.
Yukiko TorizakiDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.
Yoko AdachiDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.
Hirofumi ShimodaDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.
Takehiro ShimadaDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.
Yasuhito SekimotoDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.
Hidejiro UrakamiDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.
Shiko SekiDepartment of Gastroenterological Surgery, National Hospital Organization Tokyo Medical Center, 2-5-1Meguro-Ku, HigashigaokaTokyo, 152-8902, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate the safety of gastrectomy for gastric cancer in oldest-old patients aged ≥ 85 years.

methodsThis study retrospectively analyzed the patients aged ≥ 85 years who diagnosed with gastric cancer between 2008 and 2022. The study patients were divided into three groups: a surgery group, an endoscopic submucosal dissection (ESD) group, and a non-surgery and non-ESD group (n = 64, 57, and 152). Surgical outcomes and 3-year overall and recurrence-free survival (OS and RFS) were investigated.

resultsIn the surgery group, the study cohort comprised 30 males and 34 females with a median age of 87 years. Distal, proximal, and total gastrectomy (DG, PG, and TG) were performed in 54, 1, and 9 patients, respectively. There were 27, 16, 17, and 4 patients with pStage I, II, III, and IV, respectively. Thirty-day morbidity with Clavien-Dindo grade ≥ 3 and 30-day mortality were 12.5% and 3.1%, respectively. Kaplan-Meier curves for the 3-year OS and RFS demonstrated that survival curves worsened with increasing pStage (p = 0.005 and p < 0.001, respectively). In multivariate analyses for the 3-year OS and RFS, TG and pStage ≥ III were independent risk factors (p = 0.028 and 0.011 in OS, p = 0.021 and 0.001 in RFS). In comparisons of 3-year OSs among the three groups in each cStage, survivals in the surgery group were consistently better than those in the non-surgery and non-ESD group in cStages I to III (p < 0.001, 0.001, and < 0.001 in cStage I, II, and III, respectively).

conclusionOur findings suggest that the radical gastrectomy for gastric cancer can be performed safely and has a chance to improve survival even in the oldest-old patients aged ≥ 85 years.

Indexed as

Endoscopic Mucosal ResectionGastrectomyStomach NeoplasmsAged, 80 and overFemaleHumansKaplan-Meier EstimateMaleNeoplasm StagingRetrospective StudiesSurvival RateTreatment OutcomeComplicationsElderlyOldOlderSurvival

Identifiers

PMID40119955

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.