Evidence map›Paper›PMID 40119771›Full record

ArticleJournal of Parkinson's disease2025

Investigating the prevalence of the G2019S mutation in Parkinson's disease among a Libyan population.

Nuri H Awayn, Sara A Hashish, Sultan A Salem, Sulieman Abod, Sana M Elgahmasi, Khalid Ouararhni, Houari Abdesselem, Ilham Y Abdi, Omar A El-Agnaf

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Genetic Landscape of Monogenic Parkinson's Disease in the African Population-A Systematic Review.Movement disorders : official journal of the Movement Disorder Society · 2026
    Pooled it
  2. Absence of theFrontiers in aging neuroscience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nuri H AwaynDepartment of Chemistry, Faculty of Sciences, University of Tripoli, Tripoli, Libya.
Sara A HashishCollege of Health and Life Sciences, Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar.ORCID 0000-0001-9843-3792
Sultan A SalemDepartment of Biochemistry, Faculty of Medicine, Zintan University, Zintan, Libya.
Sulieman AbodNeurology Department, Ali Omar Askar-Neuro Hospital, Tripoli, Libya.
Sana M ElgahmasiDepartment of Biochemistry, Faculty of medicine, University of Tripoli, Tripoli, Libya.
Khalid OuararhniGenomics Core Facility, Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar.
Houari AbdesselemProteomic Core Facility, Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar.
Ilham Y AbdiNeurological Disorder Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar.ORCID 0000-0002-8221-3338
Omar A El-AgnafNeurological Disorder Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar.ORCID 0000-0002-6850-8084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a progressive neurodegenerative disorder influenced by both environmental and genetic risk factors. This study investigates the prevalence of the

Indexed as

Genetic Predisposition to DiseaseMutationParkinson DiseaseProtein Serine-Threonine KinasesAdultAgedFemaleHumansLeucine-Rich Repeat Serine-Threonine Protein Kinase-2LibyaMaleMiddle AgedPrevalenceLeucine-Rich Repeat Serine-Threonine Protein Kinase-2LRRK2 protein, humanProtein Serine-Threonine KinasesG2019SLRRK2neurogeneticsNorth AfricaParkinson's disease

Identifiers

PMID40119771
PMCPMC13347441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.