Evidence map›Paper›PMID 40119432›Full record

ArticleBMC health services research2025

The budget impact analysis of nicotine replacement therapy among patients who smoke tobacco and have mental illness in South Africa and the implications.

Basetsana Maphanga, Moliehi Matlala, Rajesh Vagiri, Brian Godman, Letlhogonolo Makhele

Abstract read
In one paragraph

Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Basetsana MaphangaSchool of Pharmacy, Sefako Makgatho Health Sciences University, Molotlegi St., Ga-Rankuwa, Pretoria, 0208, South Africa.
Moliehi MatlalaSchool of Pharmacy, Sefako Makgatho Health Sciences University, Molotlegi St., Ga-Rankuwa, Pretoria, 0208, South Africa.
Rajesh VagiriDepartment of Pharmacy, Faculty of Health Sciences, University of Limpopo, Mankweng, Limpopo Province, 0727, South Africa.ORCID http://orcid.org/0000-0003-0564-7594
Brian GodmanDepartment of Pharmacoepidemiology, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK.ORCID http://orcid.org/0000-0001-6539-6972
Letlhogonolo MakheleSchool of Pharmacy, Sefako Makgatho Health Sciences University, Molotlegi St., Ga-Rankuwa, Pretoria, 0208, South Africa. Letlhogonolo.makhele@smu.ac.za.ORCID http://orcid.org/0000-0002-2689-663X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTobacco use is the world's leading preventable cause of death, with the highest burden in low and middle-income countries (LMICs). Those who have mental illness are particularly vulnerable, with a smoking rate two to five times higher than that of the general population. Quitting smoking has demonstrated benefits for mental health, including reducing stress and improving the quality of life. However, the economic feasibility of introducing Nicotine Replacement Therapy (NRT) in the psychiatric medical environment in South Africa has not yet been explored. This study aims to address this gap by assessing the impact on the budget of implementing an NRT-based smoking cessation program in a psychiatric hospital.

methodsThis retrospective and cross-sectional study followed a budget impact analysis framework. Data were retrieved between May 19 and Aug 18, 2023, from 214 patients' medical records. Using primary and secondary data, an ingredients costing approach was used to estimate direct treatment costs of NRT smoking cessation. All costs were expressed in ZAR (South African currency). The economic evaluation was conducted from the payer's perspective, and the results were reported at a 5% discount rate. A two-way 10% sensitivity analysis was conducted.

resultsThe study showed that study participants were primarily black, male, unemployed, diagnosed with schizophrenia and smoked lightly (69.16% ±3.46). Implementing the 3-month treatment period of NRT smoking cessation program would result in an expenditure of R1 478 915.42 for 214 patients. The hospital will require an additional 0.15% (±0.0095) of the total hospital budget and 6.09% (±0.31) of the hospital pharmacy budget.

conclusionOur findings indicate that while implementing a NRT is crucial for improving the overall health outcomes among patients with mental illnesses, substantial investment would be required. The budgetary allocation for NRT smoking cessation interventions would vary by treatment settings and program duration. Consequently, careful consideration of budget allocation and resource distribution is necessary to ensure the program's sustainability within the broader healthcare framework in South Africa.

Indexed as

BudgetsMental DisordersSmoking CessationTobacco Use Cessation DevicesAdultCross-Sectional StudiesFemaleHospitals, PsychiatricHumansMaleMiddle AgedNicotine Replacement TherapyRetrospective StudiesSouth AfricaBudget impact analysisMental healthNicotine replacement therapyPsychiatric hospitalsSmoking cessationSouth Africa

Identifiers

PMID40119432
PMCPMC11927220

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.