ArticleParasites & vectors2025
Prevalence of anti-Trypanosoma cruzi and anti-Leishmania infantum antibodies in domestic dogs from Tremedal, Bahia: insights from the Oxente Chagas Bahia Project.
Article in Parasites & vectors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Canine exposure to vector-borne pathogens in a rural Brazilian landscape.Veterinary research communications · 2026Article
- Evaluation of four chimeric Trypanosoma cruzi recombinant antigens for serological diagnosis of chronic Chagas disease in dogs: a phase II study.Parasites & vectors · 2025Article
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9 authors.
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Abstract
backgroundChagas disease (CD) and visceral leishmaniasis (VL) are two important zoonotic diseases that present significant public health challenges in Latin America. Domestic dogs, due to their close contact with humans, serve as key reservoirs for both Trypanosoma cruzi (the causative agent of CD) and Leishmania infantum (the causative agent of VL), making them important sentinels in disease surveillance. This study, conducted as part of the Oxente Chagas Bahia Project, aimed to assess the seroprevalence of anti-T. cruzi and anti-L. infantum antibodies in domestic dogs from Tremedal, Bahia, Brazil.
methodsSerum samples from 17 dogs were analyzed using indirect enzyme-linked immunosorbent assay (ELISA) (using recombinant antigens (IBMP-8.1, IBMP-8.2, IBMP-8.3, IBMP-8.4) for T. cruzi and the TR DPP® rapid test and ELISA for L. infantum.
resultsThe results showed that 5.9% (1/17) of the dogs tested were seropositive for T. cruzi, indicating the presence of the parasite in the region. Similarly, 5.9% (1/17) of the dogs were confirmed to be positive for L. infantum by ELISA, although the results of the TR DPP® test initially suggested a higher prevalence (41.2%), highlighting the risk of false-positive results.
conclusionsThese findings underscore the critical role of dogs in CD and VL surveillance, given their involvement in both domestic and peridomestic transmission cycles. The study also emphasizes the need for confirmatory testing to ensure diagnostic accuracy, which will contribute to more effective disease control strategies in endemic areas. This work highlights the importance of a One Health approach in which human and animal health are closely monitored to mitigate the transmission of zoonotic diseases.
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