Evidence map›Paper›PMID 40119365›Full record

SynthesisBMC oral health2025

Systematic review and meta-analysis of the prevalence of oral cancer in Nigeria.

Ucheoma Nwaozuru, Chisom Obiezu-Umeh, Somtochukwu Anthonia Uzodufa, Abideen Salako, Folahanmi Tomiwa Akinsolu, Oliver Chukwujekwu Ezechi, Titilola Gbajabiamila, Francisca Nwaokorie, Omolola Titilayo Alade, George Uchenna Eleje and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ucheoma NwaozuruCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria. Unwaozur@wakehealth.edu.
Chisom Obiezu-UmehCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Somtochukwu Anthonia UzodufaUniversity of Nigeria Teaching Hospital, Nsukka, Nigeria.
Abideen SalakoCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Folahanmi Tomiwa AkinsoluCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Oliver Chukwujekwu EzechiCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Titilola GbajabiamilaCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Francisca NwaokorieDepartment of Medical Laboratory Science, College of Medicine, University of Lagos, Lagos, Nigeria.
Omolola Titilayo AladeDepartment of Preventive and Community Dentistry, Faculty of Dentistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
George Uchenna ElejeCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Joanne LusherCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Morẹ Nikẹ Oluwátóyìn FoláyanCenter for Reproduction and Population Health Studies, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOral cancer is ranked among the ten most common cancers in the world and is a growing public health concern in Nigeria. However, the extent of the burden of oral cancer in Nigeria is poorly understood. A better understanding of the prevalence of oral cancer will inform the development and implementation of efficient and effective oral cancer prevention and management strategies. This systematic review and meta-analysis aimed to estimate the prevalence of oral cancer in Nigeria to guide relevant oral health interventions and policies.

methodsWe searched PubMed, Embase, Scopus, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Web of Science for studies published from 1990 until August 15, 2023. We included cohort, cross-sectional, case-control, descriptive, and interventional studies that reported prevalence data for oral cancer in Nigeria. The primary outcome was the pooled prevalence of oral cancer. Meta-analysis was performed using the random effect model. The Higgins inconsistency index -I

resultsIn total, 3025 articles were screened, and data from 7 studies with a total sample size of 9188 (1702 oral cancer cases) were included in the meta-analysis. Participants age ranged from 0 to 100 years. Oral cancer prevalence varied across the studies, ranging from 7.5% to 41%. The pooled prevalence of oral cancer in Nigeria was 20% (95% confidence interval, CI:0.11-0.28, I

conclusionsThe current analysis indicates an overall pooled oral cancer prevalence of 20% in Nigeria. The high burden of oral cancer in Nigeria highlights a need for public health interventions and policies to promote the prevention and early detection of oral cancer. The analysis also shows a higher prevalence of oral cancer among men. Population-based studies are necessary to better understand individual differences in oral cancer.

Indexed as

Mouth NeoplasmsHumansNigeriaPrevalenceMeta-analysisNigeriaOral CancerPrevalence

Identifiers

PMID40119365
PMCPMC11927334

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.