Evidence map›Paper›PMID 40119147›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Correlation between abdominal visceral fat and laryngopharyngeal reflux in patients with obstructive sleep apnea.

Xiangrong Cao, Yanru Duan, Yibo Hao, Zhe Wang, Chenhai Zheng, Zhiming Zhang, Jie Qin, Dahai Wu

Abstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Abdominal visceral fat and laryngopharyngeal reflux in patients with obstructive sleep apnea.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  2. Association Between Laryngopharyngeal Reflux and the Severity of Obstructive Sleep Apnea.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Xiangrong CaoPostgraduate Training Base of Dalian Medical University in the General Hospital of Northern Theater Command, Dalian, Liaoning, 116044, China.
Yanru DuanPostgraduate Training Base of Dalian Medical University in the General Hospital of Northern Theater Command, Dalian, Liaoning, 116044, China.
Yibo HaoPostgraduate Training Base of China Medical University in the General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
Zhe WangDepartment of Otolaryngology, General Hospital of Northern Theater Command, No.83, Wenhua Road, Shenhe District, Shenyang, Liaoning, 110016, China.
Chenhai ZhengDepartment of Otolaryngology, General Hospital of Northern Theater Command, No.83, Wenhua Road, Shenhe District, Shenyang, Liaoning, 110016, China.
Zhiming ZhangDepartment of Otolaryngology, General Hospital of Northern Theater Command, No.83, Wenhua Road, Shenhe District, Shenyang, Liaoning, 110016, China.
Jie QinDepartment of Otolaryngology, General Hospital of Northern Theater Command, No.83, Wenhua Road, Shenhe District, Shenyang, Liaoning, 110016, China.
Dahai WuDepartment of Otolaryngology, General Hospital of Northern Theater Command, No.83, Wenhua Road, Shenhe District, Shenyang, Liaoning, 110016, China. dhwudoc@163.com.ORCID http://orcid.org/0000-0003-0649-0656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo research the correlation between abdominal visceral fat and laryngopharyngeal reflux (LPR) in patients with obstructive sleep apnea (OSA).

methodsThis study included 72 OSA patients, and the correlation between abdominal visceral fat and the severity of LPR was analyzed after abdominal visceral fat area (VFA) was measured according to body composition analysis and reflux symptom index (RSI) score was completed. Finally, in order to further clarify the effect of VFA on LPR, multiple linear regression analysis was performed on the collected related parameters.

resultsPartial correlation analysis showed that the VFA was positively correlated with the RSI score (r = 0.502, p < 0.001) after controlling for apnea-hypopnea index (AHI), body mass index (BMI), lowest oxygen saturation (LSO₂), age, and sex. The multiple linear regression analysis indicated that VFA and AHI were the factors influencing LPR (t = 4.678, p < 0.001; t = 3.164, p = 0.002).

conclusionOur study found that VFA was associated with RSI score in OSA patients, but BMI didn't show an independent correlation with RSI score. This indicated that we should pay attention to the effect of abdominal visceral fat on LPR in OSA patients, and more experiments are needed in the future to clarify the relationship between the two.

Indexed as

Intra-Abdominal FatLaryngopharyngeal RefluxSleep Apnea, ObstructiveAdultBody Mass IndexFemaleHumansMaleMiddle AgedPolysomnographySeverity of Illness IndexAbdominal visceral fatAbdominal visceral fat areaLaryngopharyngeal refluxLPRObstructive sleep apneaOSAVFA

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.