Evidence map›Paper›PMID 40119116›Full record

ArticleEye (London, England)2025

Status of papillomacular bundle in optic disc pit associated with maculopathy.

Dmitrii S Maltsev, Alexei N Kulikov, Yana A Kalinicheva, Daniela Bacherini, Jay Chhablani

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Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Dmitrii S MaltsevDepartment of Ophthalmology, S.M. Kirov Medical Academy, 21, Botkinskaya str., 194044, St. Petersburg, Russia. glaz.med@yandex.ru.ORCID http://orcid.org/0000-0001-6598-3982
Alexei N KulikovDepartment of Ophthalmology, S.M. Kirov Medical Academy, 21, Botkinskaya str., 194044, St. Petersburg, Russia.
Yana A KalinichevaDepartment of Ophthalmology, S.M. Kirov Medical Academy, 21, Botkinskaya str., 194044, St. Petersburg, Russia.
Daniela BacheriniOphthalmology Department, Careggi University Hospital, University of Florence, Florence, Italy.
Jay ChhablaniUniversity of Pittsburgh, UPMC Eye Center, 1622 Locust St, Pittsburgh, PA, 15219, USA.ORCID http://orcid.org/0000-0003-1772-3558

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the status of papillomacular bundle (PMB) in eyes with optic disc pit.

methodsElectronical medical records and optical coherence tomography (OCT) data of patients with optic disc pit were retrospectively reviewed. The PMB defect was measured on structural en face OCT projections. Length of ellipsoid zone defect (EZD) in the centre of the macula was measured on a horizontal cross-sectional scan passing through the centre of the fovea. Correlation between parameters under study, central retinal thickness (CRT), and visual acuity was calculated.

resultsThirteen eyes of thirteen patients (seven males and six females, mean age 31.3 ± 11.6 years) with optic disc pit and maculopathy and two eyes of two patients without maculopathy (2 females, 21 and 23 years) were included. The defect of PMB was found in 12 out 13 eyes (92.3%) with maculopathy. In those eyes EZD was found in 11 out of 13 eyes (84.6%). Among 12 eyes with PMB defect, 11 eyes had EZD (92.6%), one eye had PMB defect without EZD, while no eyes had EZD without PMB defect (p = 0.01). Mean PMB defect width was 0.86 ± 0.64 mm. Mean length of EZD was 425 ± 423 µm. The length of EZD and PMB width were highly correlated (r = 0.71, p < 0.001). Two eyes without maculopathy demonstrated no papillomacular bundle defect.

conclusionPapillomacular bundle defect may be one of the essential characteristics in the optic disc pit with maculopathy and can be associated with the alteration of the central retina in these eyes.

Indexed as

Eye AbnormalitiesMacula LuteaOptic DiskRetinal DiseasesRetinal Ganglion CellsAdolescentAdultFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, Optical CoherenceVisual AcuityYoung Adult

Identifiers

PMID40119116
PMCPMC12130218

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