Evidence map›Paper›PMID 40119075›Full record

Observational studyPediatric nephrology (Berlin, Germany)2025

Feasibility of peritoneal dialysis and survival outcomes following laparotomy in children with kidney failure: a single-center, retrospective, observational study in Japan.

Tomoya Kaneda, Kentaro Nishi, Naoki Shimojima, Tetsuya Ishimaru, Misaki Akiyama, Satoshi Okada, Masao Ogura, Kentaro Ide, Akihiro Yoneda, Seisuke Sakamoto and 2 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tomoya KanedaDivision of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, 157-8535, Japan.
Kentaro NishiDivision of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, 157-8535, Japan. nishi-k@ncchd.go.jp.ORCID 0000-0002-3436-0392
Naoki ShimojimaDivision of Surgery, National Center for Child Health and Development, Tokyo, Japan.
Tetsuya IshimaruDivision of Surgery, National Center for Child Health and Development, Tokyo, Japan.
Misaki AkiyamaDivision of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, 157-8535, Japan.
Satoshi OkadaDivision of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, 157-8535, Japan.
Masao OguraDivision of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, 157-8535, Japan.
Kentaro IdeCritical Care Medicine, National Center for Child Health and Development, Tokyo, Japan.
Akihiro YonedaDivision of Surgery, National Center for Child Health and Development, Tokyo, Japan.
Seisuke SakamotoOrgan Transplantation Center, National Center for Child Health and Development, Tokyo, Japan.
Kenji IshikuraDepartment of Pediatrics, Kitasato University School of Medicine, Kanagawa, Japan.
Koichi KameiDivision of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, 157-8535, Japan.

Funding

Public Foundation of Vaccination Research CenterTaiju Life Social Welfare Foundation
6 · The paper itself

Abstract

backgroundChildren with kidney failure may have congenital or acquired gastrointestinal comorbidities requiring laparotomy, which can complicate the initiation/continuation of peritoneal dialysis (PD) because of peritoneal adhesions.

methodsThis retrospective observational study included patients younger than 18 years who initiated PD after laparotomy or underwent laparotomy after PD initiation between February 1, 2006, and July 31, 2024. The primary endpoint was post-laparotomy PD failure, and the secondary endpoint was death. The characteristics and surgical details of patients categorized based on PD success after laparotomy were compared.

resultsThe study included 21 of the 22 eligible patients with kidney failure who underwent laparotomy, after the exclusion of one patient who did not resume postoperative PD. The median age at laparotomy was 1.5 (interquartile range [IQR], 0.3-15.7) months, and the median age at postoperative PD commencement was 5.3 (IQR, 1.3-13.0) months. PD failure occurred in five of the seven patients with bowel resection compared to none of the 14 patients without bowel resection (P = 0.001). In all cases, PD failure was associated with extensive small bowel or sigmoid colon resection. PD was successfully performed after other procedures, including colostomy alone, hepatectomy, and liver transplantation. The cause of death was septic shock in all four young patients who died, and postoperative sepsis was significantly associated with mortality.

conclusionsIn children with kidney failure, PD is generally feasible after laparotomy, except in cases involving extensive bowel resection. Effective infection control is crucial to improve survival after laparotomy, especially in younger infants.

Indexed as

LaparotomyPeritoneal DialysisPostoperative ComplicationsRenal InsufficiencyChildChild, PreschoolFeasibility StudiesFemaleHumansInfantJapanMaleRetrospective StudiesTissue AdhesionsTreatment OutcomeBowel resectionChildrenCongenital anomalies of the kidney and urinary tractLaparotomyPeritoneal dialysis

Identifiers

PMID40119075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.