Evidence map›Paper›PMID 40118978›Full record

ArticleScientific reports2025

Assessment of hazardous trace metals and associated health risk as affected by feed intake in buffalo milk.

Samun Shahzad, Kamran Ashraf, Nusrat Ehsan, Khawar Sultan, Asim Abbasi, Sobia Tabassum, Amina Muzamil, Nazih Y Rebouh, Qamar Uz Zaman

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samun ShahzadDepartment of Environmental Sciences, The University of Lahore, Lahore, 54590, Pakistan.
Kamran AshrafState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, People's Republic of China.
Nusrat EhsanLahore Business School, The University of Lahore, Lahore, 54590, Pakistan.
Khawar SultanDepartment of Environmental Sciences, The University of Lahore, Lahore, 54590, Pakistan.
Asim AbbasiDepartment of Entomology, University of Agriculture, Faisalabad, 38040, Pakistan.
Sobia TabassumDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Amina MuzamilDepartment of Environmental Sciences, The University of Lahore, Lahore, 54590, Pakistan.
Nazih Y RebouhDepartment of Environmental Management Institute of Environmental Engineering, RUDN University, 6 Mi-klukho-Maklaya St, Moscow, 117198, Russia.
Qamar Uz ZamanDepartment of Environmental Sciences, The University of Lahore, Lahore, 54590, Pakistan. qamar.zaman1@envs.uol.edu.pk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of hazardous trace metals in the food chain poses a significant risk to human health. Milk is an essential part of a balanced dietary regimen, playing a crucial role in supporting optimal growth and development of the human body. However, the continuous consumption of metal-contaminated milk might potentially lead to the onset of chronic health disorders. The objective of this study was to investigate the fluctuation of physico-chemical attributes and concentrations of toxic trace metals in buffalo milk and examine their relationship with various feed types (alfalfa fodder, maize silage, and a combination of fodder and silage). Additionally, the study attempted to determine the potential health hazards that these levels may offer to consumers. The study revealed that the characteristics of the milk, such as its physical, chemical, and metallic properties, were affected by the type of feed. The measured physicochemical properties encompassed pH values ranging from 5.12 to 9.13, electrical conductivity values ranging from 995 to 1799 µS/cm, total solids content ranging from 10.12 to 15.9 mg/L, moisture content ranging from 84.5% to 90%, density ranging from 17.2 to 30.29 g/mL, and fat content ranging from 3.9% to 10.9%. The metal concentrations varied within the following ranges: lead (0.00229-0.029 mg/L), cadmium (0.00122-0.058 mg/L), mercury (0.00101-0.03 mg/L), and arsenic (0.0007-0.198 mg/L). Significant positive associations were found between the levels of metals and the types of feed. Principal component analysis identified the considerable influence of certain feed categories on the metal concentration found in the milk. While certain estimated daily intake (EDI) and health risk index (HRI) values surpassed suggested criteria, the hazard index (HI) values remained within safe ranges. This indicates that the total risk of metal ingestion through milk consumption is modest. It is crucial to continuously check the presence of both organic and inorganic pollutants in milk, and regulatory agencies should implement stringent procedures to prevent contamination.

Indexed as

Animal FeedFood ContaminationMetals, HeavyMilkTrace ElementsAnimalsBuffaloesHumansRisk AssessmentMetals, HeavyTrace ElementsBuffalo milkFeed categoryFodder typesImpactsMetallic contents; SilageQuality

Identifiers

PMID40118978
PMCPMC11928531

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.