Evidence map›Paper›PMID 40118942›Full record

ArticleScientific data2025

The interplay between brain and behavior during development: A multisite effort to generate and share simulated datasets.

Neda Sadeghi, Isabelle F van der Velpen, Bradley T Baker, Ishaan Batta, Kyle J Cahill, Sarah Genon, Ethan McCormick, Léa C Michel, Dustin Moraczewski, Masoud Seraji and 13 more

Abstract readDataset
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Neda Sadeghi *Section on Social and Cognitive Developmental Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.ORCID http://orcid.org/0000-0002-5213-1614
Isabelle F van der Velpen *Section on Social and Cognitive Developmental Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.
Bradley T BakerTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA.
Ishaan BattaTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA.
Kyle J CahillTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA.
Sarah GenonInstitute of Neuroscience and Medicine (INM-7), Research Centre Jülich, Jülich, Germany.ORCID http://orcid.org/0000-0002-7087-7882
Ethan McCormickMethodology and Statistics Department, Institute of Psychology, Leiden University, Leiden, The Netherlands.
Léa C MichelDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.
Dustin MoraczewskiData Science and Sharing Team, National Institute of Mental Health, National Institutes Health, Bethesda, USA.
Masoud SerajiTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA.
Philip ShawKing's Maudsley Partnership for Child and Young People, King's College London, London, UK.ORCID http://orcid.org/0000-0002-1313-2526
Rogers F SilvaTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA.
Najme SoleimaniTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA.
Emma SprootenDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.
Øystein SørensenCenter for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0003-0724-3542
Adam G ThomasData Science and Sharing Team, National Institute of Mental Health, National Institutes Health, Bethesda, USA.ORCID http://orcid.org/0000-0002-2850-1419
Audrey ThurmNeurodevelopmental and Behavioral Phenotyping Service, National Institute of Mental Health, National Institutes of Health, Bethesda, USA.
Zi-Xuan ZhouDevelopmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Faculty of Psychology, Beijing Normal University, Beijing, China.ORCID http://orcid.org/0000-0002-9894-7934
Vince D CalhounTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, Georgia, USA.ORCID http://orcid.org/0000-0001-9058-0747
Rogier KievitDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.
Anna PlachtiInstitute of Neuroscience and Medicine (INM-7), Research Centre Jülich, Jülich, Germany.
Xi-Nian ZuoDevelopmental Population Neuroscience Research Center, IDG/McGovern Institute for Brain Research, Faculty of Psychology, Beijing Normal University, Beijing, China.ORCID http://orcid.org/0000-0001-9110-585X
Tonya WhiteSection on Social and Cognitive Developmental Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA. tonya.white@nih.gov.

Funding

Research within the Section on Social and Cognitive Developmental Neuroscience ZIAMH002986 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI WHITE, TONYA · 2023 to 2025
$6.3M
Deutsche Forschungsgemeinschaft (German Research Foundation) DFG, GE 2835/2-1, GE 2835/4-1Intramural NIH HHS ZIA MH002986
6 · The paper itself

Abstract

One of the challenges in the field of neuroimaging is that we often lack knowledge about the underlying truth and whether our methods can detect developmental changes. To address this gap, five research groups around the globe created simulated datasets embedded with their assumptions of the interplay between brain development, cognition, and behavior. Each group independently created the datasets, unaware of the approaches and assumptions made by the other groups. Each group simulated three datasets with the same variables, each with 10,000 participants over 7 longitudinal waves, ranging from 7 to 20 years-of-age. The independently created datasets include demographic data, brain derived variables along with behavior and cognition variables. These datasets and code that were used to generate the datasets can be downloaded and used by the research community to apply different longitudinal models to determine the underlying patterns and assumptions where the ground truth is known.

Indexed as

BehaviorBrainAdolescentChildCognitionHumansNeuroimagingYoung Adult

Identifiers

PMID40118942
PMCPMC11928570

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.