Evidence map›Paper›PMID 40118937›Full record

ArticleScientific reports2025

An interrupted time series study of the leprosy case detection in Brazil after the COVID-19 pandemic.

George Jó Bezerra Sousa, Daniele Dos Santos Lages, Patrícia Pereira Lima Barbosa, Margarida Cristiana Napoleão Rocha, Sebastião Alves de Sena Neto, Jurema Guerrieri Brandão, Francisco Carlos Félix Lana, Carlos Henrique Alencar, Maria Lúcia Duarte Pereira, Alda Maria da Cruz and 1 more

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

George Jó Bezerra SousaGeneral Coordination of Surveillance of Leprosy and Diseases in Elimination, Department of Transmitted Diseases, Ministry of Health, SRTVN Quadra 701 Lote D, Edifício, PO 700, Brasília, 70719-040, Brazil. george.sousa@saude.gov.br.
Daniele Dos Santos LagesLeprosy Coordination, Minas Gerais Health Secretary, Belo Horizonte, Brazil.
Patrícia Pereira Lima BarbosaGeneral Coordination of Surveillance of Leprosy and Diseases in Elimination, Department of Transmitted Diseases, Ministry of Health, SRTVN Quadra 701 Lote D, Edifício, PO 700, Brasília, 70719-040, Brazil.
Margarida Cristiana Napoleão RochaGeneral Coordination of Surveillance of Leprosy and Diseases in Elimination, Department of Transmitted Diseases, Ministry of Health, SRTVN Quadra 701 Lote D, Edifício, PO 700, Brasília, 70719-040, Brazil.
Sebastião Alves de Sena NetoGeneral Coordination of Surveillance of Leprosy and Diseases in Elimination, Department of Transmitted Diseases, Ministry of Health, SRTVN Quadra 701 Lote D, Edifício, PO 700, Brasília, 70719-040, Brazil.
Jurema Guerrieri BrandãoGeneral Coordination of Surveillance of Leprosy and Diseases in Elimination, Department of Transmitted Diseases, Ministry of Health, SRTVN Quadra 701 Lote D, Edifício, PO 700, Brasília, 70719-040, Brazil.
Francisco Carlos Félix LanaSchool of Nursing, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Carlos Henrique AlencarDeparment of Public Health, Federal University of Ceará, Fortaleza, Brazil.
Maria Lúcia Duarte PereiraFaculty of Nursing, Ceará State University, Fortaleza, Brazil.
Alda Maria da CruzDepartment of Transmitted Diseases, Ministry of Health, Brasília, Brazil.
Ciro Martins GomesGeneral Coordination of Surveillance of Leprosy and Diseases in Elimination, Department of Transmitted Diseases, Ministry of Health, SRTVN Quadra 701 Lote D, Edifício, PO 700, Brasília, 70719-040, Brazil.

Funding

Conselho Nacional de Desenvolvimento Cientifico e Tecnologico 445040/2023-8Departamento de Ciência e Tecnologia, da Secretaria de Ciência, Tecnologia, Inovação e Complexo da Saúde, do Ministério da Saúde 21/2023
6 · The paper itself

Abstract

COVID-19 pandemics affected several health systems processes, including leprosy care. This study aimed to estimate the impact of the COVID-19 pandemic on the leprosy case detection rate in Brazil from 2017 to 2022. Data was retrieved from Sinan, a Brazilian notification system, and monthly leprosy detection rate in the overall population and in individuals under 15 years of age were the main outcomes. The series was interrupted in February 2020, when the COVID-19 public health emergency was declared in Brazil. The data were analysed via Prais-Winsten regression. Over the 72 months analysed, the COVID-19 pandemic led to an immediate 0.55 reduction (95% CI 0.48-0.62) in the overall leprosy detection rate, with a subsequent monthly increase of 1.01 (95% CI 1.00-1.02). For the population under 15 years of age, the pandemic caused an immediate 0.48 reduction (95% CI 0.40-0.57), followed by a monthly increase of 1.01 (95% CI 1.01-1.02) after the onset of the pandemic. Subnational analysis revealed that most federative units followed the trend for the overall detection rate, but high heterogeneity was observed regarding individuals under 15 years of age. Therefore, it is urgent to target strategies to minimize delayed diagnosis and long-term consequences of leprosy.

Indexed as

COVID-19LeprosyAdolescentAdultBrazilChildChild, PreschoolFemaleHumansInterrupted Time Series AnalysisMaleMiddle AgedPandemicsSARS-CoV-2Young AdultCOVID-19EpidemiologyHansen’s diseaseInterrupted time series analysisLeprosy

Identifiers

PMID40118937
PMCPMC11928467

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.