ArticleScientific reports2025
Optical coherence tomography angiography compared with optical coherence tomography for detection of glaucoma progression with high myopia.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Deep Learning and Radiomics Assessment for Highly Myopic Glaucoma Detection Based on Fundus Photography.Ophthalmology science · 2026Article
- GCIPL color coding on OCT predicts glaucoma conversion in normal-tension glaucoma suspects, including a high myopia subgroup.Scientific reports · 2026Article
- Glaucoma detection in myopic eyes using deep learning autoencoder-based regions of interest.Frontiers in ophthalmology · 2025Article
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Authors and funding
3 authors.
Funding
Abstract
Little is known about the change of macular and peripapillary vessel density comparing to macular ganglion cell-inner plexiform layer (mGCIPL) thickness or peripapillary retinal nerve fiber layer (pRNFL) thickness in high myopic glaucoma in the longitudinal follow-up. A total of 62 glaucoma patients with high myopia (71 eyes) were analyzed over an average follow-up of 2.88 years, with at least four optical coherence tomography angiography (OCTA) imaging sessions. Among the participants, 47 eyes exhibited stable visual fields, while 24 eyes showed progression. We compared the longitudinal changes between the macular/peripapillary vessel density (VD) and the mGCIPL/pRNFL thickness in the two groups. Our results indicated a significantly greater decline in the macular and peripapillary VD in the progressive group compared to the stable group. (all p < 0.05) However, there were no significant differences in the rate of changes of mGCIPL thickness or the pRNFL thickness between the two groups. Overall, this study demonstrates that VD decreases are detectable over time in the highly myopic glaucoma patients. OCTA could be considered in the imaging algorithm in the follow up of glaucoma progression in the highly myopic patients.
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