Evidence map›Paper›PMID 40118631›Full record

ArticleJACC. Case reports2025

Volume Rendering of CT Images to Inform Closure of Complex Ventricular Septal Defects.

Alana R Cianciulli, Analise Sulentic, Yan Wang, Matthew Daemer, Silvani Amin, Jeremiah Joyce, Andras Lasso, Hansel J Otero, Meryl S Cohen, Stephanie Fuller and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alana R CianciulliDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Analise SulenticDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Yan WangDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Matthew DaemerDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Silvani AminDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jeremiah JoyceDivision of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania, USA; Department of Pediatrics Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Andras LassoLaboratory for Percutaneous Surgery, Queens University, Kingston, Ontario, Canada.
Hansel J OteroDepartment of Radiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Meryl S CohenDivision of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania, USA; Department of Pediatrics Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Stephanie FullerDivision of Pediatric Cardiac Surgery, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Mohammad A K NuriDivision of Pediatric Cardiac Surgery, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jessica TangDivision of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania, USA; Department of Pediatrics Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Michael L O'ByrneDivision of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania, USA; Department of Pediatrics Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Matthew A JolleyDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Division of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania, USA; Department of Pediatrics Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: JOLLEYM@chop.edu.

Funding

Computer Modeling of the Tricuspid Valve in Hypoplastic Left Heart SyndromeR01HL153166 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI JOLLEY, MATTHEW · 2020 to 2024
$3.7M
NHLBI NIH HHS R01 HL153166
6 · The paper itself

Abstract

The anatomy of structurally complex ventricular septal defects (SC-VSD) can be difficult to assess using 2-dimensional (2D) images and traditional 2D multiplanar views of 3D images. Direct identification and visualization are not always possible via the standard tricuspid approach in surgical repair. Volume rendering is a near instant method for 3D visualization of computed tomography angiography images, but application of this method to the planning of SC-VSD closure has not been described. We describe the integration of virtual patch and device placement within volume-rendered computed tomography angiography images within SlicerHeart to inform surgical and transcatheter closure of SC-VSDs in 3 patients. Virtual heart models were created and examined by a multidisciplinary team. Virtual device placement and surgical patch design was applied to better inform patient candidacy and procedural planning. Volume rendering-based visualization of SC-VSDs is feasible and may inform understanding of anatomy and conceptualization of the optimal repair. Further study is needed to demonstrate improvement in outcomes.

Indexed as

3-dimensional imagingcomputed tomographyimagingventricular septal defect

Identifiers

PMID40118631
PMCPMC12011141

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.