Evidence map›Paper›PMID 40118581›Full record

ArticleBritish journal of anaesthesia2025

Solving the enigma of burst suppression.

Jyun-You Liou, M Bruce Maciver, Jamie W Sleigh

Abstract readEditorial
In one paragraph

Article in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jyun-You LiouDepartment of Anesthesiology, Weill Cornell Medicine, New York, NY, USA. Electronic address: jyl9010@med.cornell.edu.
M Bruce MaciverDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Jamie W SleighDepartment of Anaesthesia, Waikato Clinical Campus, University of Auckland, Hamilton, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neural mechanisms underlying burst suppression during anaesthesia remain poorly understood. A recent study in the British Journal of Anaesthesia used calcium imaging to examine neuronal activity driving burst suppression in both cortical and subcortical structures. The results reveal diverse involvement of cortical excitatory neurones in burst suppression, while distinct interneurone subtypes play varied roles. Parvalbumin neurones in particular are key in modulating these rhythms. These insights will inform anaesthetic management of patients with neurological vulnerabilities.

Indexed as

AnesthesiaNeuronsAnimalsHumansburst suppressioncalcium imagingGABA interneuronesisofluraneneuronal synchrony

Identifiers

PMID40118581
PMCPMC11947557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.