Evidence map›Paper›PMID 40118143›Full record

ArticleContemporary clinical trials2025

A study protocol to engage religious leaders to reduce blood pressure in Tanzanian communities: A cluster randomized trial.

Bazil Kavishe, Megan Willkens, Agrey H Mwakisole, Fredrick Kalokola, Elialilia Okello, Philip Ayieko, Edmund Kisanga, Myung Hee Lee, Saidi Kapiga, Jennifer A Downs and 1 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bazil KavisheMwanza Intervention Trials Unit, Mwanza, National Institute for Medical Research, Mwanza, Tanzania.
Megan WillkensCenter for Global Health, Weill Cornell Medicine, New York, NY, USA.
Agrey H MwakisoleMwanza Intervention Trials Unit, Mwanza, National Institute for Medical Research, Mwanza, Tanzania; Mwanza Christian College, Mwanza, Tanzania.
Fredrick KalokolaCatholic University of Health and Allied Sciences, Weill Bugando School of Medicine, Mwanza, Tanzania.
Elialilia OkelloMwanza Intervention Trials Unit, Mwanza, National Institute for Medical Research, Mwanza, Tanzania.
Philip AyiekoMwanza Intervention Trials Unit, Mwanza, National Institute for Medical Research, Mwanza, Tanzania; London School of Hygiene and Tropical Medicine, London, UK.
Edmund KisangaMwanza Intervention Trials Unit, Mwanza, National Institute for Medical Research, Mwanza, Tanzania.
Myung Hee LeeCenter for Global Health, Weill Cornell Medicine, New York, NY, USA.
Saidi KapigaMwanza Intervention Trials Unit, Mwanza, National Institute for Medical Research, Mwanza, Tanzania; London School of Hygiene and Tropical Medicine, London, UK.
Jennifer A DownsMwanza Intervention Trials Unit, Mwanza, National Institute for Medical Research, Mwanza, Tanzania; Center for Global Health, Weill Cornell Medicine, New York, NY, USA.
Robert PeckMwanza Intervention Trials Unit, Mwanza, National Institute for Medical Research, Mwanza, Tanzania; Center for Global Health, Weill Cornell Medicine, New York, NY, USA. Electronic address: rnp2002@med.cornell.edu.

Funding

Engaging Religious Leaders to Reduce Blood Pressures in Tanzanian CommunitiesR01HL161673 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jennifer Alzos Downs, Robert N Peck · 2022 to 2026
$2.6M
Post-Doctoral Fellowship Training in HIV Clinical InvestigationD43TW011826 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI Daniel W Fitzgerald, Saidi Kapiga · 2021 to 2026
$1.9M
Schistosomiasis and Women's Reproductive HealthK24AI182638 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jennifer Alzos Downs · 2024 to 2026
$611k
Patient-Oriented Research in Global Cardiovascular Diseases and Interactions with HIVK24HL170902 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Robert N Peck · 2023 to 2026
$504k
FIC NIH HHS D43 TW011826NHLBI NIH HHS K24 HL170902NHLBI NIH HHS R01 HL161673NIAID NIH HHS K24 AI182638
6 · The paper itself

Abstract

backgroundMost people with hypertension in Sub-Saharan Africa are unaware of their status. Low perceived need for hypertension screening, low trust in biomedical health care, unhealthy norms for diet and exercise, and prioritization of spiritual over physical health are key barriers to blood pressure (BP) control in Tanzanian communities. We seek to determine whether engaging religious leaders to screen for hypertension and educate communities on cardiovascular health can lead to a sustained community BP reduction.

methodsThis trial aims to determine the efficacy of an intervention that engages religious leaders to reduce BP in Tanzanian communities. After refinement of the intervention following pilot testing, a hybrid type I randomized control trial will be conducted across 20 rural communities (10 intervention and 10 control communities). The intervention will consist of educational sessions for religious leaders, equipping them to provide community cardiovascular health teachings, and BP screening organized jointly by religious leaders and health care workers. We will measure the reduction in mean community BP and changes in hypertension awareness and treatment, diet, physical activity, body mass index, and waist circumference after one year. Key elements that contribute to the intervention's implementation and effectiveness to strengthen its adoption and broader use during and after the intervention up to 24 months will be evaluated. DISCUSSION: Community-level barriers to BP control inhibit awareness and treatment of hypertension in Tanzania. Through innovative partnerships with trusted religious leaders, we seek to study an intervention with the potential to reduce BP and improve overall community health.

Indexed as

HypertensionBlood PressureBody Mass IndexDietExerciseFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMass ScreeningRandomized Controlled Trials as TopicRural PopulationTanzaniaBlood pressureRandomized control trialReligious leadersTanzania

Identifiers

PMID40118143
PMCPMC11994286

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.