Evidence map›Paper›PMID 40117959›Full record

ReviewThe American journal of emergency medicine2025

High risk and low incidence diseases: Aneurysmal subarachnoid hemorrhage.

Christian R Gerhart, Aaron J Lacy, Brit Long, Alex Koyfman, Charles E Kircher

Abstract readReview
In one paragraph

Review in The American journal of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian R GerhartDepartment of Emergency Medicine, Washington University, School of Medicine, 660 S. Euclid Ave, St. Louis, MO, USA. Electronic address: c.gerhart@wustl.edu.
Aaron J LacyDepartment of Emergency Medicine, Washington University, School of Medicine, 660 S. Euclid Ave, St. Louis, MO, USA.
Brit LongSAUSHEC, Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, USA. Electronic address: Brit.long@yahoo.com.
Alex KoyfmanDepartment of Emergency Medicine, UT Southwester, Dallas, TX, USA.
Charles E KircherDepartment of Emergency Medicine, Washington University, School of Medicine, 660 S. Euclid Ave, St. Louis, MO, USA. Electronic address: charles.kircher@wustl.edu.

Funding

Mid-America Regional Coordinating Center (MARCC)U24NS107230 · NINDS · WASHINGTON UNIVERSITY · PI Andria Lee Ford, Peter David Panagos · 2018 to 2026
$2.8M
NINDS NIH HHS U24 NS107230
6 · The paper itself

Abstract

introductionAneurysmal subarachnoid hemorrhage (aSAH) is a serious condition that carries a high rate of morbidity.

objectiveThis review highlights the pearls and pitfalls of aSAH, including presentation, diagnosis, and management in the emergency department based on current evidence. DISCUSSION: aSAH is a type of hemorrhagic stroke, most commonly from rupture of a saccular aneurysm, which results in leakage of blood into the subarachnoid space. It presents acutely and has many mimics, making the diagnosis difficult. Patients who present with either sentinel or acute presentation of a headache that is described as sudden or severe, has associated neck stiffness, cranial nerve deficits, syncope, seizure, and/or coma should raise suspicion for the diagnosis. Non-contrast head computed tomography is the imaging modality of choice for evaluation and diagnosis of the disease in patients who present acutely. Further diagnostic testing with lumbar puncture or advanced neuroimaging may be required in patients who present >6 h after symptom onset. Patients with aSAH require critical, multidisciplinary care, with particular attention to management of airway, breathing, and circulation; expeditious referral for neurosurgical intervention; coagulopathy reversal; and prophylaxis against downstream complications.

conclusionAn understanding of aSAH can assist emergency clinicians in diagnosing and managing this disease.

Indexed as

Subarachnoid HemorrhageEmergency Service, HospitalHumansIncidenceNeuroimagingRisk FactorsTomography, X-Ray ComputedAneurysmHeadacheIntracranial hemorrhageNeurologic deficitNeurologyOttawa SAH ruleSAHStrokeSubarachnoid hemorrhageVascular

Identifiers

PMID40117959
PMCPMC12534557

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.