Article in Science immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
17 authors.
Weili XuCenter for Immunity and Inflammation, Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID 0000-0002-6040-2883
Natasha B GolovchenkoCenter for Immunity and Inflammation, Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID 0000-0001-8323-4643
Irving U Martínez-VargasDepartment of Pathology, Molecular and Cell-Based Medicine and Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Andrew FongCenter for Immunity and Inflammation, Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.
Prateeksha RoutDepartment of Genetics, Human Genetics Institute of New Jersey, Rutgers, the State University of New Jersey, Piscataway, NJ, USA.
Sajan AchiDepartment of Pathology, Molecular and Cell-Based Medicine and Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Edie B BucarSaban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.ORCID 0009-0002-5842-6664
Jonathan J HsiehSaban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-7213-7992
Kaylynn J VidmarDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID 0009-0007-1439-7554
Lanjing ZhangDepartment of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA.ORCID 0000-0001-5436-887X
Alexandros D PolydoridesDepartment of Pathology, Molecular and Cell-Based Medicine and Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-8604-0756
Immo PrinzInstitute of Immunology, Hannover Medical School, Hanover, Germany.ORCID 0000-0002-8789-9578
George KolliasInstitute for Fundamental Biomedical Research, Biomedical Sciences Research Center "Alexander Fleming," Vari, Greece.ORCID 0000-0003-1867-3150
Mark R FreySaban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-2561-5402
Theresa T PizarroDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID 0000-0003-3163-915X
Michael P VerziDepartment of Genetics, Human Genetics Institute of New Jersey, Rutgers, the State University of New Jersey, Piscataway, NJ, USA.ORCID 0000-0003-4082-4330
Karen L EdelblumCenter for Immunity and Inflammation, Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID 0000-0001-8288-4898
Funding
The Cleveland Digestive Diseases Research Core Center (DDRCC)P30DK097948 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Fabio Cominelli · 2015 to 2026
$15.6M
The role of the ErbB4 and ErbB3 neuregulin receptors in intestinal epithelial regenerationR01DK095004 · NIDDK · CHILDREN'S HOSPITAL OF LOS ANGELES · PI FREY, MARK R · 2013 to 2022
$3.5M
Mechanisms Driving Metabolic Shifts in the Intestinal EpitheliumR01DK126446 · NIDDK · RUTGERS, THE STATE UNIV OF N.J. · PI VERZI, MICHAEL P. · 2021 to 2025
$2.1M
gd IELs in chronic ileitisR01DK135272 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Karen Leigh Edelblum · 2023 to 2026
$1.9M
The role of SPRY2 in the colonic epithelial response to inflammationR01DK119694 · NIDDK · CHILDREN'S HOSPITAL OF LOS ANGELES · PI FREY, MARK R · 2019 to 2022
$1.5M
BD FACSAria II for NJMS Flow Cytometry CoreS10RR027022 · NCRR · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI FITZGERALD-BOCARSLY, PATRICIA · 2011 to 2011
$501k
Microbiota-gamma delta IEL-Paneth cell axis in host antimicrobial responseR21AI171959 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI EDELBLUM, KAREN LEIGH · 2022 to 2023
$439k
Intraepithelial lymphocyte regulation of epithelial cell sheddingR21AI143892 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI EDELBLUM, KAREN LEIGH · 2019 to 2020
Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IELs) provide immunosurveillance of the intestinal barrier but are reduced in patients with active Crohn's disease (CD). Here, we report an underappreciated role for γδ IELs in maintaining immunological tolerance during the onset and progression of CD-like ileitis using TNF
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn's disease-like ileitis. · full record | OpenQuestion